Andrew D. Miranker
Affiliations: | Molecular Biophysics and Biochemistry | Yale University, New Haven, CT |
Area:
Protein Folding and Dynamics, Structural BiologyWebsite:
http://medicine.yale.edu/mbb/faculty/andrew_miranker.profileGoogle:
"Andrew D. Miranker"Bio:
http://miranker.sites.yale.edu/
Mean distance: 7.81 | S | N | B | C | P |
Parents
Sign in to add mentor| Martin Karplus | grad student | 1992 | Harvard | |
| (Studies of molecular association phenomena : drug design and protein folding) | ||||
| Christopher M. Dobson | post-doc | Cambridge | ||
Children
Sign in to add trainee| Kevin C. Slep | grad student | 2000 | Yale |
| Jennifer L. Hall | grad student | 2003 | Yale |
| Shae B. Padrick | grad student | 2003 | Yale |
| Catherine M. Eakin | grad student | 2005 | Yale |
| Jefferson D. Knight | grad student | 2001-2006 | Yale |
| Bon W. Koo | grad student | 2007 | Yale |
| Amy M. Ruschak | grad student | 2008 | Yale |
| Jessica A. Williamson | grad student | 2008 | Yale |
| Matthew F. Calabrese | grad student | 2009 | Yale |
| Dorottya V. Blaho | grad student | 2010 | Yale |
| James A. Hebda | grad student | 2011 | Yale |
| Nicholas B. Last | grad student | 2005-2012 | Yale |
| Marisa A. Rubio | grad student | 2014 | Yale |
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Publications
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| Wójcik S, Birol M, Rhoades E, et al. (2018) Targeting the Intrinsically Disordered Proteome Using Small-Molecule Ligands. Methods in Enzymology. 611: 703-734 |
| Birol M, Kumar S, Rhoades E, et al. (2018) Conformational switching within dynamic oligomers underpins toxic gain-of-function by diabetes-associated amyloid. Nature Communications. 9: 1312 |
| Birol M, Kumar S, Rhoades E, et al. (2017) Toxic and Non-Toxic Forms of Membrane Poration are Mediated by Structurally Distinct States of Islet Amyloid Polypeptide Biophysical Journal. 112: 503a |
| Kumar S, Birol M, Schlamadinger DE, et al. (2016) Foldamer-mediated manipulation of a pre-amyloid toxin. Nature Communications. 7: 11412 |
| Kumar S, Birol M, Miranker AD. (2016) Foldamer scaffolds suggest distinct structures are associated with alternative gains-of-function in a preamyloid toxin. Chemical Communications (Cambridge, England) |
| Junghans A, Watkins EB, Majewski J, et al. (2016) Influence of the Human and Rat Islet Amyloid Polypeptides on Structure of Phospholipid Bilayers: Neutron Reflectometry and Fluorescence Microscopy Studies. Langmuir : the Acs Journal of Surfaces and Colloids |
| Khemtemourian L, Gazit E, Miranker A. (2016) Recent Insight in Islet Amyloid Polypeptide Morphology, Structure, Membrane Interaction, and Toxicity in Type 2 Diabetes. Journal of Diabetes Research. 2016: 2535878 |
| White EM, Miranker AD. (2015) A solenoid design for assessing determinants of parallel β-sheet registration. Protein Engineering, Design & Selection : Peds |
| Witten J, Ruschak A, Poterba T, et al. (2015) Mapping Protein Conformational Landscapes under Strongly Native Conditions with Hydrogen Exchange Mass Spectrometry. The Journal of Physical Chemistry. B. 119: 10016-24 |
| Nath A, Schlamadinger DE, Rhoades E, et al. (2015) Structure-Based Small Molecule Modulation of a Pre-Amyloid State: Pharmacological Enhancement of IAPP Membrane-Binding and Toxicity. Biochemistry. 54: 3555-64 |