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Andrew D. Miranker

Affiliations: 
Molecular Biophysics and Biochemistry Yale University, New Haven, CT 
Area:
Protein Folding and Dynamics, Structural Biology
Website:
http://medicine.yale.edu/mbb/faculty/andrew_miranker.profile
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"Andrew D. Miranker"
Bio:

http://miranker.sites.yale.edu/

Mean distance: 7.81
 
SNBCP

Parents

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Martin Karplus grad student 1992 Harvard
 (Studies of molecular association phenomena : drug design and protein folding)
Christopher M. Dobson post-doc Cambridge

Children

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Kevin C. Slep grad student 2000 Yale
Jennifer L. Hall grad student 2003 Yale
Shae B. Padrick grad student 2003 Yale
Catherine M. Eakin grad student 2005 Yale
Jefferson D. Knight grad student 2001-2006 Yale
Bon W. Koo grad student 2007 Yale
Amy M. Ruschak grad student 2008 Yale
Jessica A. Williamson grad student 2008 Yale
Matthew F. Calabrese grad student 2009 Yale
Dorottya V. Blaho grad student 2010 Yale
James A. Hebda grad student 2011 Yale
Nicholas B. Last grad student 2005-2012 Yale
Marisa A. Rubio grad student 2014 Yale
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Publications

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Wójcik S, Birol M, Rhoades E, et al. (2018) Targeting the Intrinsically Disordered Proteome Using Small-Molecule Ligands. Methods in Enzymology. 611: 703-734
Birol M, Kumar S, Rhoades E, et al. (2018) Conformational switching within dynamic oligomers underpins toxic gain-of-function by diabetes-associated amyloid. Nature Communications. 9: 1312
Birol M, Kumar S, Rhoades E, et al. (2017) Toxic and Non-Toxic Forms of Membrane Poration are Mediated by Structurally Distinct States of Islet Amyloid Polypeptide Biophysical Journal. 112: 503a
Kumar S, Birol M, Schlamadinger DE, et al. (2016) Foldamer-mediated manipulation of a pre-amyloid toxin. Nature Communications. 7: 11412
Kumar S, Birol M, Miranker AD. (2016) Foldamer scaffolds suggest distinct structures are associated with alternative gains-of-function in a preamyloid toxin. Chemical Communications (Cambridge, England)
Junghans A, Watkins EB, Majewski J, et al. (2016) Influence of the Human and Rat Islet Amyloid Polypeptides on Structure of Phospholipid Bilayers: Neutron Reflectometry and Fluorescence Microscopy Studies. Langmuir : the Acs Journal of Surfaces and Colloids
Khemtemourian L, Gazit E, Miranker A. (2016) Recent Insight in Islet Amyloid Polypeptide Morphology, Structure, Membrane Interaction, and Toxicity in Type 2 Diabetes. Journal of Diabetes Research. 2016: 2535878
White EM, Miranker AD. (2015) A solenoid design for assessing determinants of parallel β-sheet registration. Protein Engineering, Design & Selection : Peds
Witten J, Ruschak A, Poterba T, et al. (2015) Mapping Protein Conformational Landscapes under Strongly Native Conditions with Hydrogen Exchange Mass Spectrometry. The Journal of Physical Chemistry. B. 119: 10016-24
Nath A, Schlamadinger DE, Rhoades E, et al. (2015) Structure-Based Small Molecule Modulation of a Pre-Amyloid State: Pharmacological Enhancement of IAPP Membrane-Binding and Toxicity. Biochemistry. 54: 3555-64
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