Yorgo E. Modis

Affiliations: 
Molecular Biophysics and Biochemistry Yale University, New Haven, CT 
Area:
molecular mechanisms of host-pathogen interactions using X-ray crystallography, microscopy, and other biophysical and biochemical approaches
Website:
http://medicine.yale.edu/mbb/faculty/yorgo_modis.profile
Google:
"Yorgo E. Modis"
Bio:

http://www.linkedin.com/pub/yorgo-modis/29/214/52

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Publications

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Reikine S, McLaughlin SH, Modis Y. (2020) Equilibrium Binding Model for CpG DNA-Dependent Dimerization of Toll-like Receptor 9 Ectodomain. Biochemistry
Cader MZ, de Almeida Rodrigues RP, West JA, et al. (2020) FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle. Cell. 180: 278-295.e23
Cader MZ, Rodrigues RPdA, West JA, et al. (2020) FAMIN is a purine nucleoside enzyme that paces cellular metabolism via the purine nucleotide cycle Cell
Stoll GA, Oda S, Chong Z, et al. (2019) Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing Proceedings of the National Academy of Sciences of the United States of America. 116: 15042-15051
Yu Q, Qu K, Modis Y. (2018) Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis. Molecular Cell. 72: 999
Douse CH, Liu Y, Bloor S, et al. (2018) Neuropathic mutations in MORC2 perturb GHKL ATPase dimerization dynamics and transcriptional control by multiple structural mechanisms Nature Communications
Meyer PA, Socias S, Key J, et al. (2016) Data publication with the structural biology data grid supports live analysis. Nature Communications. 7: 10882
Prigozhin DM, Modis Y. (2016) Flunarizine arrests hepatitis C virus membrane fusion Hepatology. 63: 14-16
Wong EV, Cao W, Vörös J, et al. (2015) Pi release limits the intrinsic and RNA-stimulated ATPase cycles of DEAD-box protein 5 (Dbp5). Journal of Molecular Biology
Zhang X, Li S, Modis Y, et al. (2015) Functional assessment and structural basis of antibody binding to human papillomavirus capsid. Reviews in Medical Virology
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