Marius Pop
Affiliations: | 2014-2016 | Biological Engineering | Massachusetts Institute of Technology, Cambridge, MA, United States |
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Publications
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| Freeman DB, Hopkins TD, Mikochik PJ, et al. (2023) Discovery of KB-0742, a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of CDK9 for MYC-Dependent Cancers. Journal of Medicinal Chemistry |
| Richters A, Doyle SK, Freeman DB, et al. (2020) Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors. Cell Chemical Biology |
| Akande OE, Damle PK, Pop M, et al. (2019) DBC1 Regulates p53 Stability via Inhibition of CBP-Dependent p53 Polyubiquitination. Cell Reports. 26: 3323-3335.e4 |
| Struntz NB, Chen A, Deutzmann A, et al. (2019) Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription. Cell Chemical Biology |
| Sandoval GJ, Pulice JL, Pakula H, et al. (2018) Binding of TMPRSS2-ERG to BAF Chromatin Remodeling Complexes Mediates Prostate Oncogenesis. Molecular Cell |
| Boskovic ZV, Kemp MM, Freedy AM, et al. (2016) Inhibition of zinc-dependent histone deacetylases with a chemically triggered electrophile. Acs Chemical Biology |
| Doyle SK, Pop MS, Evans HL, et al. (2015) Advances in discovering small molecules to probe protein function in a systems context. Current Opinion in Chemical Biology. 30: 28-36 |
| Pop MS, Wassaf D, Koehler AN. (2014) Probing small-molecule microarrays with tagged proteins in cell lysates. Current Protocols in Chemical Biology. 6: 209-20 |
| Theurillat JP, Udeshi ND, Errington WJ, et al. (2014) Prostate cancer. Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer. Science (New York, N.Y.). 346: 85-89 |
| Pop MS, Stransky N, Garvie CW, et al. (2014) A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein. Molecular Cancer Therapeutics. 13: 1492-502 |