Hang Hubert Yin

1995-1999 Applied Chemistry Peking University, Beijing, Beijing Shi, China 
 1999-2004 Chemistry Yale University, New Haven, CT 
 2004-2007 Biochemistry and Biophysics University of Pennsylvania Medical School, Philadelphia, PA, United States 
 2007-2018 Chemistry and BIochemistry University of Colorado, Boulder, Boulder, CO, United States 
 2018- School of Pharmaceutical Sciences Tsinghua National University, Beijing, Beijing Shi, China 
Chemical Biology, Drug Discovery
"Hang Hubert Yin"
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Jiang X, Yuan Y, Huang J, et al. (2020) Structural Basis for Blocking Sugar Uptake into the Malaria Parasite Plasmodium falciparum. Cell
Wang Y, Zhang S, Li H, et al. (2020) Small-Molecule Modulators of Toll-like Receptors. Accounts of Chemical Research
Jiang S, Tanji H, Yin K, et al. (2020) Rationally designed small-molecule inhibitors targeting an unconventional pocket on the TLR8 protein-protein interface. Journal of Medicinal Chemistry
Russell AE, Sneider A, Witwer KW, et al. (2019) Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop. Journal of Extracellular Vesicles. 8: 1684862
Padilla-Salinas R, Anderson R, Sakaniwa K, et al. (2019) Discovery of Novel Small Molecule Dual Inhibitors Targeting Toll-like Receptor 7 and 8. Journal of Medicinal Chemistry
Peng Y, Zhang X, Zhang T, et al. (2019) Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain. Brain, Behavior, and Immunity
Zhang Y, Jin X, Liang J, et al. (2019) Extracellular vesicles derived from ODN-stimulated macrophages transfer and activate Cdc42 in recipient cells and thereby increase cellular permissiveness to EV uptake. Science Advances. 5: eaav1564
Tamura R, Balabanova A, Frakes SA, et al. (2019) Photoactivatable Prodrug of Doxazolidine Targeting Exosomes. Journal of Medicinal Chemistry
Hu Z, Tanji H, Jiang S, et al. (2018) Small-Molecule TLR8 Antagonists via Structure-Based Rational Design. Cell Chemical Biology
Sammond DW, Kastelowitz N, Donohoe BS, et al. (2018) An iterative computational design approach to increase the thermal endurance of a mesophilic enzyme. Biotechnology For Biofuels. 11: 189
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