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Alan C. Cheng

Affiliations: 
Brandeis University, Waltham, MA, United States 
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Alan D. Frankel grad student 2002 UCSF
 (Strategies for specific recognition of RNA using hydrogen bonding.)

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Cheng AC, Doherty EM, Johnstone S, et al. (2019) Structure-guided discovery of dual recognition chemibodies Acta Crystallographica Section A. 75
Cheng AC, Doherty EM, Johnstone S, et al. (2018) Structure-guided Discovery of Dual-recognition Chemibodies. Scientific Reports. 8: 7570
Loving KA, Lin A, Cheng AC. (2014) Structure-based druggability assessment of the mammalian structural proteome with inclusion of light protein flexibility. Plos Computational Biology. 10: e1003741
Gustin DJ, Li Y, Brown ML, et al. (2013) Structure guided design of a series of sphingosine kinase (SphK) inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 4608-16
Huang H, La DS, Cheng AC, et al. (2012) Structure- and property-based design of aminooxazoline xanthenes as selective, orally efficacious, and CNS penetrable BACE inhibitors for the treatment of Alzheimer's disease. Journal of Medicinal Chemistry. 55: 9156-69
Bryan MC, Whittington DA, Doherty EM, et al. (2012) Rapid development of piperidine carboxamides as potent and selective anaplastic lymphoma kinase inhibitors. Journal of Medicinal Chemistry. 55: 1698-705
Liu JJ, Cheng AC, Tang HL, et al. (2011) Benzodiazepinone Derivatives as CRTH2 Antagonists. Acs Medicinal Chemistry Letters. 2: 515-8
Schenkel LB, Huang X, Cheng A, et al. (2011) Discovery of potent and highly selective thienopyridine Janus kinase 2 inhibitors. Journal of Medicinal Chemistry. 54: 8440-50
Peterson ML, Stanton MK, Kelly RC, et al. (2011) Preparation, solid state characterization, and single crystal structure analysis of N-(4-(6-(4-(trifluoromethyl)phenyl)pyrimidin-4-yloxy)benzo[d] thiazol-2-yl)acetamide crystal forms Crystengcomm. 13: 1170-1180
Cee VJ, Schenkel LB, Hodous BL, et al. (2010) Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor. Journal of Medicinal Chemistry. 53: 6368-77
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