Amanda E. Hargrove, Ph.D.
Affiliations: | 2005-2010 | Chemistry | University of Texas, Austin, Texas |
| 2010-2013 | Chemistry | California Institute of Technology, Pasadena, CA | |
| 2013- | Chemistry | Duke University, Durham, NC |
Area:
Bio-organic chemistryWebsite:
https://chem.duke.edu/labs/hargrove/amanda-hargroveGoogle:
"Amanda Hargrove"Bio:
C.V. (pdf) https://chem.duke.edu/sites/chem.duke.edu/files/uploads//hargrove/Hargrove_CV_170114_0.pdf
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Parents
Sign in to add mentor| Eric V. Anslyn | grad student | 2005-2010 | UT Austin |
| Jonathan L. Sessler | grad student | 2005-2010 | UT Austin |
| Peter B. Dervan | post-doc | 2010-2013 | Caltech |
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Publications
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| Bailey MA, Martyr JG, Hargrove AE, et al. (2024) Stability-Based Proteomics for Investigation of Structured RNA-Protein Interactions. Analytical Chemistry |
| Wicks SL, Morgan BS, Wilson AW, et al. (2023) Probing Bioactive Chemical Space to Discover RNA-Targeted Small Molecules. Biorxiv : the Preprint Server For Biology |
| Bagnolini G, Luu TB, Hargrove AE. (2023) Recognizing the power of machine learning and other computational methods to accelerate progress in small molecule targeting of RNA. Rna (New York, N.Y.) |
| Zafferani M, Martyr JG, Muralidharan D, et al. (2022) Multiassay Profiling of a Focused Small Molecule Library Reveals Predictive Bidirectional Modulation of the lncRNA MALAT1 Triplex Stability . Acs Chemical Biology |
| Zafferani M, Muralidharan D, Montalvan NI, et al. (2022) RT-qPCR as a screening platform for mutational and small molecule impacts on structural stability of RNA tertiary structures. Rsc Chemical Biology. 3: 905-915 |
| Donlic A, Swanson EG, Chiu LY, et al. (2022) R-BIND 2.0: An Updated Database of Bioactive RNA-Targeting Small Molecules and Associated RNA Secondary Structures. Acs Chemical Biology. 17: 1556-1566 |
| Cai Z, Zafferani M, Akande OM, et al. (2022) Quantitative Structure-Activity Relationship (QSAR) Study Predicts Small-Molecule Binding to RNA Structure. Journal of Medicinal Chemistry. 65: 7262-7277 |
| Zafferani M, Haddad C, Luo L, et al. (2021) Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures. Science Advances. 7: eabl6096 |
| Cable J, Heard E, Hirose T, et al. (2021) Noncoding RNAs: biology and applications-a Keystone Symposia report. Annals of the New York Academy of Sciences |
| Zafferani M, Hargrove AE. (2021) Small molecule targeting of biologically relevant RNA tertiary and quaternary structures. Cell Chemical Biology |