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David Gani, Ph.D

2009- Principal's Office University of Strathclyde, Glasgow, Scotland, United Kingdom 
"David Gani"

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Rutherford TJ, Wilkie J, Vu CQ, et al. (2001) NMR studies and semi-empirical energy calculations for cyclic ADP-ribose. Nucleosides, Nucleotides & Nucleic Acids. 20: 1485-95
Tai CH, Burkhard P, Gani D, et al. (2001) Characterization of the allosteric anion-binding site of O-acetylserine sulfhydrylase. Biochemistry. 40: 7446-52
Miller DJ, Beaton MW, Wilkie J, et al. (2000) The 6-OH group of D-inositol 1-phosphate serves as an H-bond donor in the catalytic hydrolysis of the phosphate ester by inositol monophosphatase. Chembiochem : a European Journal of Chemical Biology. 1: 262-71
Schulz J, Beaton MW, Gani D. (2000) Synthesis of (+)-(1R, 2R, 4R, 6S)-1, 6-epoxy-4-benzyloxycyclohexan2-ol, a key precursor to inositol monophosphatase inhibitors, from (-)-quinic acid Journal of the Chemical Society, Perkin Transactions 1. 943-954
Gani D, Archer CH, Botting NP, et al. (1999) The 3-methylaspartase reaction probed using 2H- and 15N-isotope effects for three substrates: a flip from a concerted to a carbocationic amino-enzyme elimination mechanism upon changing the C-3 stereochemistry in the substrate from R to S. Bioorganic & Medicinal Chemistry. 7: 977-90
Pollard JR, Richardson S, Akhtar M, et al. (1999) Mechanism of 3-methylaspartase probed using deuterium and solvent isotope effects and active-site directed reagents: identification of an essential cysteine residue. Bioorganic & Medicinal Chemistry. 7: 949-75
Ryan MD, Donnelly M, Lewis A, et al. (1999) A model for nonstoichiometric, cotranslational protein scission in eukaryotic ribosomes Bioorganic Chemistry. 27: 55-79
Schulz J, Wilkie J, Beaton MW, et al. (1998) Preparation and properties of 6-substituted cyclohexane-1,2,4-triol derivatives: mechanistic probes for the inositol monophosphatase reaction. Biochemical Society Transactions. 26: 315-22
Lewis A, Rutherford TJ, Wilkie J, et al. (1998) Design, construction and properties of peptide N-terminal cap templates devised to initiate α-helices. Part 3. Caps derived from N-[(2S)-2-chloropropionyl]-(2S)-Pro-(2R)-Ala-(2S,4S)-4-thioPro-OMe Journal of the Chemical Society - Perkin Transactions 1. 3795-3806
Lewis A, Ryan MD, Gani D. (1998) Design, construction and properties of peptide N-terminal cap templates devised to initiate α-helices. Part 1. Caps derived from N-(4-chlorobutyryl)-(2S)-Pro-(2S)-Pro-(2S)-Ala-OMe and N-[(2S)-2-chloropropionyl]-(2S)-Pro-(2S)-Pro-(2S,4S)-4-hydroxyPro-OMe Journal of the Chemical Society - Perkin Transactions 1. 3767-3775
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