Rajat Rohatgi

Oncology Stanford University School of Medicine, Palo Alto, CA, United States 
Biochemical Mechanisms of Hedgehog (Hh) Signaling
"Rajat Rohatgi"


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Jack W. Szostak research assistant 1992-1994 Harvard Medical School
 (Non-Enzymatic Template-Directed Ligation Reactions of Ribooligonucleotides)
Marc W. Kirschner grad student 1997-2002 Harvard
 (Biochemical dissection of a signaling pathway that controls actin assembly.)
Matthew P. Scott post-doc 2005-2008 Stanford Medical School
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Dubey R, van Kerkhof P, Jordens I, et al. (2020) R-spondins engage heparan sulfate proteoglycans to potentiate WNT signaling. Elife. 9
Patel BB, Lebensohn AM, Pusapati GV, et al. (2019) Discovery of gene regulatory elements through a new bioinformatics analysis of haploid genetic screens. Plos One. 14: e0198463
Lebensohn AM, Rohatgi R. (2018) R-spondins can potentiate WNT signaling without LGRs. Elife. 7
Lebensohn AM, Dubey R, Neitzel LR, et al. (2016) Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling. Elife. 5
Byrne EF, Sircar R, Miller PS, et al. (2016) Structural basis of Smoothened regulation by its extracellular domains. Nature
Zhao Z, Lee RT, Pusapati GV, et al. (2016) An essential role for Grk2 in Hedgehog signalling downstream of Smoothened. Embo Reports
Marada S, Navarro G, Truong A, et al. (2015) Functional Divergence in the Role of N-Linked Glycosylation in Smoothened Signaling. Plos Genetics. 11: e1005473
Niewiadomski P, Rohatgi R. (2015) Rapid Screening of Gli2/3 Mutants Using the Flp-In System. Methods in Molecular Biology (Clifton, N.J.). 1322: 125-30
Ahrends R, Niewiadomski P, Teruel MN, et al. (2015) Measuring Gli2 Phosphorylation by Selected Reaction Monitoring Mass Spectrometry. Methods in Molecular Biology (Clifton, N.J.). 1322: 105-23
Niewiadomski P, Rohatgi R. (2015) Measuring Expression Levels of Endogenous Gli Genes by Immunoblotting and Real-Time PCR. Methods in Molecular Biology (Clifton, N.J.). 1322: 81-92
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