James R. Halpert
Affiliations: | Pharmacy | University of California, San Diego, La Jolla, CA |
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Children
Sign in to add trainee| Emily E. Scott | post-doc | 1999-2004 | UTMB |
| Sean C. Gay | post-doc | 2008-2011 | UCSD |
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| Roberts AG, Stevens JC, Szklarz GD, et al. (2022) . Drug Metabolism and Disposition: the Biological Fate of Chemicals |
| Skopec MM, Halpert JR, Dearing MD. (2022) Mammalian cytochrome P450 biodiversity: Physiological importance, function, and protein and genomic structures of cytochromes P4502B in multiple species of woodrats with different dietary preferences. Advances in Pharmacology (San Diego, Calif.). 95: 107-129 |
| Halpert JR. (2020) So many roads traveled: A career in science and administration. The Journal of Biological Chemistry. 295: 822-832 |
| Shah MB, Zhang Q, Halpert JR. (2018) Crystal Structure of CYP2B6 in Complex with an Efavirenz Analog. International Journal of Molecular Sciences. 19 |
| Chen C, Liu J, Wilderman PR, et al. (2018) Structure-activity relationship of phenoxyaniline congener interactions with cytochrome P450 2B enzymes Drug Metabolism and Pharmacokinetics. 33: S75 |
| Chen C, Liu J, Halpert JR, et al. (2017) Use of Phenoxyaniline Analogues To Generate Biochemical Insights into the Interactio n of Polybrominated Diphenyl Ether with CYP2B Enzymes. Biochemistry |
| Huo L, Liu J, Szklarz GD, et al. (2017) Rational Re-Engineering of the Oxidation of 7-Alkoxycoumarin Derivatives by Cytochromes P450 2B from the Desert Woodrat Neotoma lepida. Biochemistry |
| Shah MB, Liu J, Zhang Q, et al. (2017) Halogen-π Interactions in the Cytochrome P450 Active Site: Structural Insights into Human CYP2B6 Substrate Selectivity. Acs Chemical Biology |
| Müller CS, Knehans T, Davydov DR, et al. (2016) Correction to Concurrent Cooperativity and Substrate Inhibition in the Epoxidation of Carbamazepine by Cytochrome P450 3A4 Active Site Mutants Inspired by Molecular Dynamics Simulations. Biochemistry |
| Shah MB, Jang HH, Wilderman PR, et al. (2016) Effect of detergent binding on cytochrome P450 2B4 structure as analyzed by X-ray crystallography and deuterium-exchange mass spectrometry. Biophysical Chemistry. 216: 1-8 |