Karl Hult, Professor

Affiliations: 
Biotechnology The Royal Inst. of Technology 
Area:
Catalysis, Enzymology, Organic Chemistry, Biochemistry
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"Karl Hult"
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Publications

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Syrén P, Joubioux FL, Henda YB, et al. (2013) Proton Shuttle Mechanism in the Transition State of Lipase‐Catalyzed N‐Acylation of Amino Alcohols Chemcatchem. 5: 1842-1853
Hamberg A, Magnusson AO, Hu FJ, et al. (2013) Selective Monoacylation of Diols by Substrate Assisted Catalysis in T40A Candida antarctica Lipase B Chemcatchem. 5: 743-747
Hamberg A, Maurer S, Hult K. (2012) Rational engineering of Candida antarctica lipase B for selective monoacylation of diols. Chemical Communications (Cambridge, England). 48: 10013-5
Syrén P, Hult K. (2011) Amidases Have a Hydrogen Bond that Facilitates Nitrogen Inversion, but Esterases Have Not Chemcatchem. 3: 853-860
Syrén PO, Hult K. (2010) Substrate conformations set the rate of enzymatic acrylation by lipases. Chembiochem : a European Journal of Chemical Biology. 11: 802-10
Vallin M, Syrén PO, Hult K. (2010) Mutant lipase-catalyzed kinetic resolution of bulky phenyl alkyl sec-alcohols: a thermodynamic analysis of enantioselectivity. Chembiochem : a European Journal of Chemical Biology. 11: 411-6
Marton Z, Léonard-Nevers V, Syrén PO, et al. (2010) Mutations in the stereospecificity pocket and at the entrance of the active site of Candida antarctica lipase B enhancing enzyme enantioselectivity Journal of Molecular Catalysis B: Enzymatic. 65: 11-17
Fransson L, Laurell A, Widyan K, et al. (2010) Minor enantiomer recycling-effect of two reinforcing catalysts on product yield and enantiomeric excess Chemcatchem. 2: 683-693
Wingstrand E, Laurell A, Fransson L, et al. (2009) Minor enantiomer recycling: Metal catalyst, organocatalyst and biocatalyst working in concert Chemistry - a European Journal. 15: 12107-12113
Veld MA, Fransson L, Palmans AR, et al. (2009) Lactone size dependent reactivity in Candida antarctica lipase B: a molecular dynamics and docking study. Chembiochem : a European Journal of Chemical Biology. 10: 1330-4
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