Zachary C. Ruhe

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2007-2012 University of California, Santa Barbara, Santa Barbara, CA, United States 
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Christopher S. Hayes grad student 2007-2012 UC Santa Barbara
 (The Role of Outer-Membrane Receptor Binding in Contact-Dependent Growth Inhibition Systems.)
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Publications

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Jensen SJ, Ruhe ZC, Williams AF, et al. (2023) Paradoxical Activation of a Type VI Secretion System Phospholipase Effector by Its Cognate Immunity Protein. Journal of Bacteriology. e0011323
Jensen SJ, Ruhe ZC, Williams AF, et al. (2023) Paradoxical activation of a type VI secretion system (T6SS) phospholipase effector by its cognate immunity protein. Biorxiv : the Preprint Server For Biology
Halvorsen TM, Garza-Sánchez F, Ruhe ZC, et al. (2021) Lipidation of Class IV CdiA Effector Proteins Promotes Target Cell Recognition during Contact-Dependent Growth Inhibition. Mbio. e0253021
Donato SL, Beck CM, Garza-Sánchez F, et al. (2020) The β-encapsulation cage of rearrangement hotspot (Rhs) effectors is required for type VI secretion. Proceedings of the National Academy of Sciences of the United States of America
Ruhe ZC, Low DA, Hayes CS. (2020) Polymorphic Toxins and Their Immunity Proteins: Diversity, Evolution, and Mechanisms of Delivery. Annual Review of Microbiology
Ruhe ZC, Subramanian P, Song K, et al. (2018) Programmed Secretion Arrest and Receptor-Triggered Toxin Export during Antibacterial Contact-Dependent Growth Inhibition. Cell. 175: 921-933.e14
Ruhe ZC, Nguyen JY, Xiong J, et al. (2017) CdiA Effectors Use Modular Receptor-Binding Domains To Recognize Target Bacteria. Mbio. 8
Ruhe ZC, Nguyen JY, Chen AJ, et al. (2016) CDI Systems Are Stably Maintained by a Cell-Contact Mediated Surveillance Mechanism. Plos Genetics. 12: e1006145
Ruhe ZC, Hayes CS, Low DA. (2015) Measuring Cell-Cell Binding Using Flow-Cytometry. Methods in Molecular Biology (Clifton, N.J.). 1329: 127-36
Willett JL, Ruhe ZC, Goulding CW, et al. (2015) Contact-dependent growth inhibition (CDI) and CdiB/CdiA two-partner secretion proteins. Journal of Molecular Biology
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