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Benjamin A. Byers, Ph.D.

Affiliations: 
2004 Georgia Institute of Technology, Atlanta, GA 
Area:
Biomedical Engineering
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Andres J Garcia grad student 2004 Georgia Tech
 (In vitro and in vivo characterization of a cell source for bone tissue engineering applications: Primary bone marrow stromal cells overexpressing the osteoblast-specific transcriptional activator Runx2/Cbfa1.)

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Publications

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Byers BA, Guldberg RE, Hutmacher DW, et al. (2006) Effects of Runx2 genetic engineering and in vitro maturation of tissue-engineered constructs on the repair of critical size bone defects. Journal of Biomedical Materials Research. Part A. 76: 646-55
Byers BA, Guldberg RE, García AJ. (2004) Synergy between genetic and tissue engineering: Runx2 overexpression and in vitro construct development enhance in vivo mineralization. Tissue Engineering. 10: 1757-66
Byers BA, García AJ. (2004) Exogenous Runx2 expression enhances in vitro osteoblastic differentiation and mineralization in primary bone marrow stromal cells. Tissue Engineering. 10: 1623-32
Gersbach CA, Byers BA, Pavlath GK, et al. (2004) Runx2/Cbfa1-genetically engineered skeletal myoblasts mineralize collagen scaffolds in vitro. Biotechnology and Bioengineering. 88: 369-78
Gersbach CA, Byers BA, Pavlath GK, et al. (2004) Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype. Experimental Cell Research. 300: 406-17
García AJ, Guldberg RE, Byers BA, et al. (2003) Addressing cell-sourcing limitations with gene therapy. Ieee Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society. 22: 65-70
Byers BA, Pavlath GK, Murphy TJ, et al. (2002) Cell-type-dependent up-regulation of in vitro mineralization after overexpression of the osteoblast-specific transcription factor Runx2/Cbfal. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 1931-44
Stephansson SN, Byers BA, García AJ. (2002) Enhanced expression of the osteoblastic phenotype on substrates that modulate fibronectin conformation and integrin receptor binding. Biomaterials. 23: 2527-34
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