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William B. Lott

Affiliations: 
Queensland University of Technology, Brisbane City, Queensland, Australia 
Area:
Organic Chemistry, Biochemistry, Inorganic Chemistry, Molecular Biology, Viirology, Nanotechnology
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"William Lott"
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Parents

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Charles B. Grissom grad student 1991-1994 University of Utah
Peter Hans von Hippel post-doc 1995-1998 University of Oregon, Eugene

Children

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Shervin Takyar grad student 1999-2002 Queensland University of Technology

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Publications

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Chinnaswamy S, Lott WB. (2012) The adenine-rich tract in the 5ʹ-end of the hepatitis C virus ORF encodes a peptide regulating the binding of the C protein to RNA. Acta Virologica. 56: 217-26
Li D, Aaskov J, Lott WB. (2011) Identification of a cryptic prokaryotic promoter within the cDNA encoding the 5' end of dengue virus RNA genome. Plos One. 6: e18197
Tumban E, Painter JM, Lott WB. (2009) Comparison between the HCV IRES domain IV RNA structure and the Iron Responsive Element. Journal of Negative Results in Biomedicine. 8: 4
Li D, Lott WB, Martyn J, et al. (2004) Differential effects on the hepatitis C virus (HCV) internal ribosome entry site by vitamin B12 and the HCV core protein. Journal of Virology. 78: 12075-81
Li D, Takyar ST, Lott WB, et al. (2003) Amino acids 1-20 of the hepatitis C virus (HCV) core protein specifically inhibit HCV IRES-dependent translation in HepG2 cells, and inhibit both HCV IRES- and cap-dependent translation in HuH7 and CV-1 cells. The Journal of General Virology. 84: 815-25
Takyar SS, Gowans EJ, Lott WB. (2002) Vitamin B12 stalls the 80 S ribosomal complex on the hepatitis C internal ribosome entry site. Journal of Molecular Biology. 319: 1-8
Lott WB, Takyar SS, Tuppen J, et al. (2001) Vitamin B12 and hepatitis C: molecular biology and human pathology. Proceedings of the National Academy of Sciences of the United States of America. 98: 4916-21
Warrilow D, Lott WB, Greive S, et al. (2000) Properties of the bovine viral diarrhoea virus replicase in extracts of infected MDBK cells. Archives of Virology. 145: 2163-71
Lott WB, Pontius BW, von Hippel PH. (1998) A two-metal ion mechanism operates in the hammerhead ribozyme-mediated cleavage of an RNA substrate. Proceedings of the National Academy of Sciences of the United States of America. 95: 542-7
Pontius BW, Lott WB, von Hippel PH. (1997) Observations on catalysis by hammerhead ribozymes are consistent with a two-divalent-metal-ion mechanism. Proceedings of the National Academy of Sciences of the United States of America. 94: 2290-4
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