Meena S. Thakur, Ph.D.

Affiliations: 
2010 University of Connecticut, Storrs, CT, United States 
Area:
Organic Chemistry
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Amy Ruth Howell grad student 2010 University of Connecticut
 (Synthesis of glycolipids for NKT cell activation and platinum catalyzed rearrangement of 4-oxaspiro[2.3]hexanes.)
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Publications

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Malapit CA, Chitale SM, Thakur MS, et al. (2015) Pt-catalyzed rearrangement of oxaspirohexanes to 3-methylenetetrahydrofurans: scope and mechanism. The Journal of Organic Chemistry. 80: 5196-209
Thakur MS, Khurana A, Kronenberg M, et al. (2014) Synthesis of a 2"-deoxy-β-GalCer. Molecules (Basel, Switzerland). 19: 10090-102
Wun KS, Cameron G, Patel O, et al. (2011) A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells. Immunity. 34: 327-39
Mallevaey T, Scott-Browne JP, Matsuda JL, et al. (2009) T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire. Immunity. 31: 60-71
Raju R, Castillo BF, Richardson SK, et al. (2009) Synthesis and evaluation of 3''- and 4''-deoxy and -fluoro analogs of the immunostimulatory glycolipid, KRN7000. Bioorganic & Medicinal Chemistry Letters. 19: 4122-5
Wun KS, Borg NA, Kjer-Nielsen L, et al. (2008) A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR. The Journal of Experimental Medicine. 205: 939-49
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