Andres E. Leschziner
Affiliations: | 2015- | Cellular and Molecular Medicine | UC San Diego Health |
Area:
structural biologyWebsite:
https://andres-leschziner.squarespace.com/config/Google:
"Andres E. Leschziner"Mean distance: 8.24 | S | N | B | C | P |
Cross-listing: StructuralBiologyTree
Parents
Sign in to add mentor| Nigel D. F. Grindley | grad student | 2000 | Yale | |
| (Structure-function studies of replicative transpositon: In vitro transposition by Tn552 transposase and the architecture of the site I synapsis of gamma delta resolvase.) | ||||
| Thomas A. Steitz | grad student | 2000 | Yale | |
| (Structure-function studies of replicative transpositon: In vitro transposition by Tn552 transposase and the architecture of the site I synapsis of gamma delta resolvase.) | ||||
| Eva Nogales | post-doc | 2007 | UC Berkeley | |
Children
Sign in to add trainee| William B. Redwine | grad student | 2012 | Stowers Instistute for Medical Research |
| Vu Q. Nguyen | grad student | 2014 | UCSD |
| Rogelio Hernandez-Lopez | grad student | 2016 | Stanford |
| Michael Cianfrocco | post-doc | 2017 | University of Michigan Medical School Ann Arbor (Cell Biology Tree) |
| Indrajit Lahiri | post-doc | 2018 | Sheffield University |
| Richard W Baker | post-doc | 2019 | University of North Carolina at Chapel Hill School of Medicine |
| Rachael Barry | post-doc | 2019 | UC Irvine |
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Publications
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| Raig ND, Surridge KJ, Sanz-Murillo M, et al. (2024) Type-II kinase inhibitors that target Parkinson's Disease-associated LRRK2. Biorxiv : the Preprint Server For Biology |
| Kendrick AA, Nguyen KHV, Ma W, et al. (2024) Cryo-EM visualizes multiple steps of dynein's activation pathway. Biorxiv : the Preprint Server For Biology |
| Dederer V, Sanz Murillo M, Karasmanis EP, et al. (2024) A designed ankyrin-repeat protein that targets Parkinson's disease-associated LRRK2. The Journal of Biological Chemistry. 300: 107469 |
| Sarsam RD, Xu J, Lahiri I, et al. (2024) Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proceedings of the National Academy of Sciences of the United States of America. 121: e2314245121 |
| Lumpkin RJ, Baker RW, Leschziner AE, et al. (2023) Author Correction: Structure and dynamics of the ASB9 CUL-RING E3 Ligase. Nature Communications. 14: 7463 |
| Reimer JM, Dickey AM, Lin YX, et al. (2023) Structure of LRRK1 and mechanisms of autoinhibition and activation. Nature Structural & Molecular Biology |
| Karasmanis EP, Reimer JM, Kendrick AA, et al. (2023) Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge. Nature Structural & Molecular Biology |
| Reimer JM, DeSantis ME, Reck-Peterson SL, et al. (2023) Structures of human dynein in complex with the lissencephaly 1 protein, LIS1. Elife. 12 |
| Snead DM, Matyszewski M, Dickey AM, et al. (2022) Structural basis for Parkinson's disease-linked LRRK2's binding to microtubules. Nature Structural & Molecular Biology. 29: 1196-1207 |
| Gillies JP, Reimer JM, Karasmanis EP, et al. (2022) Structural basis for cytoplasmic dynein-1 regulation by Lis1. Elife. 11 |