Nigel D. F. Grindley
Affiliations: | Molecular Biophysics and Biochemistry | Yale University, New Haven, CT |
Area:
DNA Replication and RepairWebsite:
http://medicine.yale.edu/mbb/faculty/research/nigel_grindley.profileGoogle:
"Nigel D. F. Grindley"Bio:
http://academy.asm.org/index.php/fellows-info/fellows-elected-in-2011/620-nigel-df-grindley
Mean distance: 8.66 | S | N | B | C | P |
Parents
Sign in to add mentorEphraim S. Anderson | grad student | 1974 | University of London |
William S. Kelley | post-doc | 1973-1975 | Carnegie Mellon |
Joan A. Steitz | post-doc | 1975-1978 | Yale |
Children
Sign in to add traineeEarl May | grad student | Yale | |
Robert E. Hughes | grad student | 1987-1992 | Yale |
Andres E. Leschziner | grad student | 2000 | Yale |
Angela M. DeLucia | grad student | 2007 | Yale |
Graham F. Hatfull | post-doc | 1984-1988 | Yale |
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Publications
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Keenholtz RA, Grindley ND, Hatfull GF, et al. (2016) Crossover-site sequence and DNA torsional stress control strand interchanges by the Bxb1 site-specific serine recombinase. Nucleic Acids Research |
Bermek O, Grindley ND, Joyce CM. (2013) Prechemistry nucleotide selection checkpoints in the reaction pathway of DNA polymerase I and roles of glu710 and tyr766. Biochemistry. 52: 6258-74 |
Hohlbein J, Aigrain L, Craggs TD, et al. (2013) Conformational landscapes of DNA polymerase I and mutator derivatives establish fidelity checkpoints for nucleotide insertion. Nature Communications. 4: 2131 |
Bai H, Kath JE, Zörgiebel FM, et al. (2012) Remote control of DNA-acting enzymes by varying the Brownian dynamics of a distant DNA end. Proceedings of the National Academy of Sciences of the United States of America. 109: 16546-51 |
Bai H, Kath J, Zorgebiel F, et al. (2012) Remote Control of DNA-Acting Enzymes by Molecular Boundary Conditions Biophysical Journal. 102: 70a |
Bai H, Sun M, Ghosh P, et al. (2011) Single-molecule analysis reveals the molecular bearing mechanism of DNA strand exchange by a serine recombinase. Proceedings of the National Academy of Sciences of the United States of America. 108: 7419-24 |
Bermek O, Grindley ND, Joyce CM. (2011) Distinct roles of the active-site Mg2+ ligands, Asp882 and Asp705, of DNA polymerase I (Klenow fragment) during the prechemistry conformational transitions. The Journal of Biological Chemistry. 286: 3755-66 |
Hohlbein J, Joyce CM, Shoolizadeh P, et al. (2011) Novel Conformational States in Mutator DNA Polymerases Observed Using Single-Molecule FRET Biophysical Journal. 100: 240a-241a |
Santoso Y, Joyce CM, Potapova O, et al. (2010) Conformational transitions in DNA polymerase I revealed by single-molecule FRET. Proceedings of the National Academy of Sciences of the United States of America. 107: 715-20 |
Torella JP, Santoso Y, Holden SJ, et al. (2010) Separating Static and Dynamic Heterogeneity in Single-Molecule FRET Experiments with Burst Variance Analysis (BVA) Biophysical Journal. 98: 591a |