Nick Carpino

Affiliations: 
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 
 Stony Brook University, Stony Brook, NY, United States 
Website:
https://medicine.stonybrookmedicine.edu/mgm/program/faculty/carpino?s=research
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"Nick Carpino"
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Publications

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Zaman A, French JB, Carpino N. (2023) The Sts Proteins: Modulators of Host Immunity. International Journal of Molecular Sciences. 24
Yin Y, Frank D, Zhou W, et al. (2020) An unexpected 2-histidine phosphoesterase activity of Suppressor of T cell receptor signaling protein-1 contributes to the suppression of cell signaling. The Journal of Biological Chemistry
Kong MS, Hashimoto-Tane A, Kawashima Y, et al. (2019) Inhibition of T cell activation and function by the adaptor protein CIN85. Science Signaling. 12
Zhou W, Yin Y, Weinheimer AS, et al. (2017) Structural and functional characterization of the histidine phosphatase domains of human Sts-1 and Sts-2. Biochemistry
Reppschläger K, Gosselin J, Dangelmaier CA, et al. (2017) TULA-2 protein phosphatase suppresses activation of Syk through the GPVI platelet receptor for collagen by dephosphorylating Tyr(P)(346), a regulatory site of Syk. The Journal of Biological Chemistry. 292: 4360
Reppschläger K, Gosselin J, Dangelmaier CA, et al. (2016) TULA-2 protein phosphatase suppresses activation of Syk through the GPVI platelet receptor for collagen by dephosphorylating pY346, a regulatory site of Syk. The Journal of Biological Chemistry
Ivanova E, Carpino N. (2016) Negative regulation of TCR signaling by ubiquitination of Zap-70 Lys-217. Molecular Immunology. 73: 19-28
Newman TN, Liverani E, Ivanova E, et al. (2014) Members of the novel UBASH3/STS/TULA family of cellular regulators suppress T-cell-driven inflammatory responses in vivo. Immunology and Cell Biology. 92: 837-50
Luis BS, Carpino N. (2014) Insights into the suppressor of T-cell receptor (TCR) signaling-1 (Sts-1)-mediated regulation of TCR signaling through the use of novel substrate-trapping Sts-1 phosphatase variants Febs Journal. 281: 696-707
San Luis B, Nassar N, Carpino N. (2013) New insights into the catalytic mechanism of histidine phosphatases revealed by a functionally essential arginine residue within the active site of the Sts phosphatases. The Biochemical Journal. 453: 27-35
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