Paul V Murphy

Affiliations: 
NUI Galway 
Area:
Organic Chemistry, Synthesis, Carbohydrates, Bioactive compounds
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"Paul Murphy"
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Publications

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Hever E, Santhanam V, Alberi S, et al. (2024) Synthesis of -glycoside analogues of isopropyl β-D-1-thiogalactopyranoside (IPTG) and 1-β-D-galactopyranosyl-2-methylpropane. Conformational analysis and evaluation as inhibitors of the lac repressor in and as galactosidase inhibitors. Organic & Biomolecular Chemistry
Dhara D, Dhara A, Bennett J, et al. (2021) Cyclisations and Strategies for Stereoselective Synthesis of Piperidine Iminosugars. Chemical Record (New York, N.Y.). 21: 2958-2979
García Caballero G, Beckwith D, Shilova NV, et al. (2020) Influence of protein (human galectin-3) design on aspects of lectin activity. Histochemistry and Cell Biology
Sweeney S, McArdle P, Taciak B, et al. (2020) Migrastatin analogues with an (E)-alkene at the ring C-3: synthesis, conformational analysis and biological evaluation Arkivoc. 2021: 51-64
Fox KA, Chadda R, Cardona F, et al. (2020) Building blocks from monosaccharides for synthesis of scaffolds, including macrocycles. Application of allylic azide rearrangement, azide-alkyne cycloaddition and ring closing metathesis Tetrahedron. 76: 131495
Chadda R, Murphy PV. (2020) Cover Feature: A Route to 1-Deoxynojirimycin and 1-Deoxymannojirimycin Derivatives with Quaternary Centers Adjacent to the Ring Nitrogen from Methyl α-d -Mannopyranoside (Eur. J. Org. Chem. 16/2020) European Journal of Organic Chemistry. 2020: 2307-2307
Chadda R, Murphy PV. (2020) A Route to 1-Deoxynojirimycin and 1-Deoxymannojirimycin Derivatives with Quaternary Centers Adjacent to the Ring Nitrogen from Methyl α-d -Mannopyranoside European Journal of Organic Chemistry. 2020: 2389-2398
Negi A, Reilly CO, Jarikote DV, et al. (2019) Multi-targeting protein-protein interaction inhibitors: Evolution of macrocyclic ligands with embedded carbohydrates (MECs) to improve selectivity. European Journal of Medicinal Chemistry. 176: 292-309
Kutzner TJ, Gabba A, FitzGerald FG, et al. (2019) How altering the modular architecture affects aspects of lectin activity: case study on human galectin-1. Glycobiology
Doyle LM, Meany FB, Murphy PV. (2019) Lewis acid promoted anomerisation of alkyl O- and S-xylo-, arabino- and fucopyranosides. Carbohydrate Research. 471: 85-94
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