Manuela Tosin

Affiliations: 
Chemistry University of Warwick, Coventry, England, United Kingdom 
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"Manuela Tosin"
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Publications

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Tosin M, Kilgour SL, Jenkins R. (2019) A photoactivatable small molecule probe for the in vivo capture of polyketide intermediates. Chemistry (Weinheim An Der Bergstrasse, Germany)
Alberti F, Leng DJ, Wilkening I, et al. (2019) Triggering the expression of a silent gene cluster from genetically intractable bacteria results in scleric acid discovery. Chemical Science. 10: 453-463
Havemann J, Yurkovich ME, Jenkins R, et al. (2017) Chemical probing of thiotetronate bio-assembly. Chemical Communications (Cambridge, England)
Tao W, Yurkovich ME, Wen S, et al. (2016) A genomics-led approach to deciphering the mechanism of thiotetronate antibiotic biosynthesis. Chemical Science. 7: 376-385
Wilkening I, Gazzola S, Riva E, et al. (2016) Second-generation probes for biosynthetic intermediate capture: towards a comprehensive profiling of polyketide assembly. Chemical Communications (Cambridge, England)
Parascandolo JS, Havemann J, Potter HK, et al. (2016) Insights into 6-Methylsalicylic Acid Bio-assembly by Using Chemical Probes. Angewandte Chemie (International Ed. in English)
Kage H, Riva E, Parascandolo JS, et al. (2015) Chemical chain termination resolves the timing of ketoreduction in a partially reducing iterative type I polyketide synthase. Organic & Biomolecular Chemistry. 13: 11414-7
Riva E, Wilkening I, Gazzola S, et al. (2014) Chemical probes for the functionalization of polyketide intermediates. Angewandte Chemie (International Ed. in English). 53: 11944-9
Tosin M, Smith L, Leadlay PF. (2011) Insights into lasalocid A ring formation by chemical chain termination in vivo. Angewandte Chemie (International Ed. in English). 50: 11930-3
Kwan DH, Tosin M, Schläger N, et al. (2011) Insights into the stereospecificity of ketoreduction in a modular polyketide synthase. Organic & Biomolecular Chemistry. 9: 2053-6
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