Manuela Tosin
Affiliations: | Chemistry | University of Warwick, Coventry, England, United Kingdom |
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Parents
Sign in to add mentorPaul V Murphy | grad student | University of Warwick | |
Peter Leadley | post-doc | 2004-2008 | Cambridge |
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Publications
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Tosin M, Kilgour SL, Jenkins R. (2019) A photoactivatable small molecule probe for the in vivo capture of polyketide intermediates. Chemistry (Weinheim An Der Bergstrasse, Germany) |
Alberti F, Leng DJ, Wilkening I, et al. (2019) Triggering the expression of a silent gene cluster from genetically intractable bacteria results in scleric acid discovery. Chemical Science. 10: 453-463 |
Havemann J, Yurkovich ME, Jenkins R, et al. (2017) Chemical probing of thiotetronate bio-assembly. Chemical Communications (Cambridge, England) |
Tao W, Yurkovich ME, Wen S, et al. (2016) A genomics-led approach to deciphering the mechanism of thiotetronate antibiotic biosynthesis. Chemical Science. 7: 376-385 |
Wilkening I, Gazzola S, Riva E, et al. (2016) Second-generation probes for biosynthetic intermediate capture: towards a comprehensive profiling of polyketide assembly. Chemical Communications (Cambridge, England) |
Parascandolo JS, Havemann J, Potter HK, et al. (2016) Insights into 6-Methylsalicylic Acid Bio-assembly by Using Chemical Probes. Angewandte Chemie (International Ed. in English) |
Kage H, Riva E, Parascandolo JS, et al. (2015) Chemical chain termination resolves the timing of ketoreduction in a partially reducing iterative type I polyketide synthase. Organic & Biomolecular Chemistry. 13: 11414-7 |
Riva E, Wilkening I, Gazzola S, et al. (2014) Chemical probes for the functionalization of polyketide intermediates. Angewandte Chemie (International Ed. in English). 53: 11944-9 |
Tosin M, Smith L, Leadlay PF. (2011) Insights into lasalocid A ring formation by chemical chain termination in vivo. Angewandte Chemie (International Ed. in English). 50: 11930-3 |
Kwan DH, Tosin M, Schläger N, et al. (2011) Insights into the stereospecificity of ketoreduction in a modular polyketide synthase. Organic & Biomolecular Chemistry. 9: 2053-6 |