Andrea Vasella
Affiliations: | Eidgenössische Technische Hochschule Zürich, Zürich, ZH, Switzerland |
Website:
https://www.chab.ethz.ch/en/the-department/people/emeriti/emeriti-homepages/andrea-vasella.htmlGoogle:
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Parents
Sign in to add mentor| Duilio Arigoni | grad student | 1971 | ETH Zürich |
| Robert B. Woodward | post-doc | ||
| Jack E. Baldwin | post-doc | 1972 | King's College |
Children
Sign in to add trainee| Eva Harth | research assistant | 1994 | Universität Zürich |
| Remi Chauvin | grad student | 1990-1993 | ETH Zürich |
| Jawad Alzeer | grad student | 1990-1995 | ETH Zürich |
| Chengzhi Cai | grad student | 1991-1996 | University of Houston |
| Alexander Ernst | grad student | 1993-1998 | ETH Zürich |
| Firouz Matloubi Moghaddam | post-doc | ETH Zürich | |
| Srinivasa-Gopalan Sampathkumar | post-doc | 1998-1999 | |
| Chepuri V. Ramana | post-doc | 1998-2001 | ETH Zürich |
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Publications
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| Pirrone MG, Gysin M, Haldimann K, et al. (2020) Predictive Analysis of the Side Chain Conformation of the Higher Carbon Sugars: Application to the Preorganization of the Aminoglycoside Ring 1 Side Chain for Binding to the Bacterial Ribosomal Decoding A Site. The Journal of Organic Chemistry |
| Sonousi A, Vasella A, Crich D. (2020) Synthesis of a Pseudotrisaccharide Suitable for Synthesis of Ring I Modified 4,5-2-Deoxystreptamine Type Aminoglycoside Antibiotics. The Journal of Organic Chemistry |
| Pirrone MG, Matsushita T, Vasella A, et al. (2020) Stereospecific synthesis of methyl 2-amino-2,4-dideoxy-6S-deuterio-α-D-xylo-hexopyranoside and methyl 2-amino-2,4-dideoxy-6S-deuterio-4-propyl-α-d-glucopyranoside: Side chain conformation of the novel aminoglycoside antibiotic propylamycin. Carbohydrate Research. 491: 107984 |
| Quirke JCK, Rajasekaran P, Sarpe VA, et al. (2019) Apralogs: Apramycin 5-O-Glycosides and Ethers with Improved Antibacterial Activity and Ribosomal Selectivity and Reduced Susceptibility to the Aminoacyltranserferase (3)-IV Resistance Determinant. Journal of the American Chemical Society |
| Sati GC, Sarpe VA, Furukawa T, et al. (2019) Modification at the 2'-Position of the 4,5-Series of 2-Deoxystreptamine Aminoglycoside Antibiotics to Resist Aminoglycoside Modifying Enzymes and Increase Ribosomal Target Selectivity. Acs Infectious Diseases |
| Sonousi A, Shcherbakov D, Vasella A, et al. (2019) Synthesis, ribosomal selectivity, and antibacterial activity of netilmicin 4'-derivatives. Medchemcomm. 10: 946-950 |
| Sarpe VA, Pirrone MG, Haldimann K, et al. (2019) Synthesis of saccharocin from apramycin and evaluation of its ribosomal selectivity. Medchemcomm. 10: 554-558 |
| Sonousi A, Sarpe VA, Brilkova M, et al. (2018) Effects of the 1-N-(4-Amino-2S-hydroxybutyryl) and 6'-N-(2-Hydroxyethyl) Substituents on Ribosomal Selectivity, Cochleotoxicity and Antibacterial Activity in the Sisomicin Class of Aminoglycoside Antibiotics. Acs Infectious Diseases |
| Mandhapati AR, Yang G, Kato T, et al. (2017) Structure-Based Design and Synthesis of Apramycin-Paromomycin Analogues. Importance of the Configuration at the 6'-Position and Differences Between the 6'-Amino and Hydroxy Series. Journal of the American Chemical Society |
| Kato T, Vasella A, Crich D. (2017) Stereospecific synthesis of methyl 2-amino-2-deoxy-(6S)-deuterio-α,β-d-glucopyranoside and methyl 2,6-diamino-2,6-dideoxy-(6R)-deuterio-α,β-d-glucopyranoside: Side chain conformations of the 2-amino-2-deoxy and 2,6-diamino-2,6-dideoxyglucopyranosides. Carbohydrate Research. 448: 10-17 |