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Eva Harth research assistant 1994 Universität Zürich
Remi Chauvin grad student 1990-1993 ETH Zürich
Jawad Alzeer grad student 1990-1995 ETH Zürich
Chengzhi Cai grad student 1991-1996 University of Houston
Alexander Ernst grad student 1993-1998 ETH Zürich
Firouz Matloubi Moghaddam post-doc ETH Zürich
Srinivasa-Gopalan Sampathkumar post-doc 1998-1999
Chepuri V. Ramana post-doc 1998-2001 ETH Zürich
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Pirrone MG, Gysin M, Haldimann K, et al. (2020) Predictive Analysis of the Side Chain Conformation of the Higher Carbon Sugars: Application to the Preorganization of the Aminoglycoside Ring 1 Side Chain for Binding to the Bacterial Ribosomal Decoding A Site. The Journal of Organic Chemistry
Sonousi A, Vasella A, Crich D. (2020) Synthesis of a Pseudotrisaccharide Suitable for Synthesis of Ring I Modified 4,5-2-Deoxystreptamine Type Aminoglycoside Antibiotics. The Journal of Organic Chemistry
Pirrone MG, Matsushita T, Vasella A, et al. (2020) Stereospecific synthesis of methyl 2-amino-2,4-dideoxy-6S-deuterio-α-D-xylo-hexopyranoside and methyl 2-amino-2,4-dideoxy-6S-deuterio-4-propyl-α-d-glucopyranoside: Side chain conformation of the novel aminoglycoside antibiotic propylamycin. Carbohydrate Research. 491: 107984
Quirke JCK, Rajasekaran P, Sarpe VA, et al. (2019) Apralogs: Apramycin 5-O-Glycosides and Ethers with Improved Antibacterial Activity and Ribosomal Selectivity and Reduced Susceptibility to the Aminoacyltranserferase (3)-IV Resistance Determinant. Journal of the American Chemical Society
Sati GC, Sarpe VA, Furukawa T, et al. (2019) Modification at the 2'-Position of the 4,5-Series of 2-Deoxystreptamine Aminoglycoside Antibiotics to Resist Aminoglycoside Modifying Enzymes and Increase Ribosomal Target Selectivity. Acs Infectious Diseases
Sonousi A, Shcherbakov D, Vasella A, et al. (2019) Synthesis, ribosomal selectivity, and antibacterial activity of netilmicin 4'-derivatives. Medchemcomm. 10: 946-950
Sarpe VA, Pirrone MG, Haldimann K, et al. (2019) Synthesis of saccharocin from apramycin and evaluation of its ribosomal selectivity. Medchemcomm. 10: 554-558
Sonousi A, Sarpe VA, Brilkova M, et al. (2018) Effects of the 1-N-(4-Amino-2S-hydroxybutyryl) and 6'-N-(2-Hydroxyethyl) Substituents on Ribosomal Selectivity, Cochleotoxicity and Antibacterial Activity in the Sisomicin Class of Aminoglycoside Antibiotics. Acs Infectious Diseases
Mandhapati AR, Yang G, Kato T, et al. (2017) Structure-Based Design and Synthesis of Apramycin-Paromomycin Analogues. Importance of the Configuration at the 6'-Position and Differences Between the 6'-Amino and Hydroxy Series. Journal of the American Chemical Society
Kato T, Vasella A, Crich D. (2017) Stereospecific synthesis of methyl 2-amino-2-deoxy-(6S)-deuterio-α,β-d-glucopyranoside and methyl 2,6-diamino-2,6-dideoxy-(6R)-deuterio-α,β-d-glucopyranoside: Side chain conformations of the 2-amino-2-deoxy and 2,6-diamino-2,6-dideoxyglucopyranosides. Carbohydrate Research. 448: 10-17
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