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Christopher S. Chen

Affiliations: 
Bioengineering University of Pennsylvania, Philadelphia, PA, United States 
Area:
Tissue Microfabrication
Website:
http://www.seas.upenn.edu/~chenlab/biography.html
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Parents

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Donald E. Ingber grad student 1997 Harvard-MIT Division of Health Sciences and Technology
 (Cell Shape and Integrins: Determinants of Extracellular Matrix Regulation of Growth and Survival)
George M. Whitesides grad student 1997 Harvard-MIT Division of Health Sciences and Technology

Children

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Christopher Lemmon grad student (BME Tree)
Celeste M. Nelson grad student 2004 Johns Hopkins
Monica Tanase grad student 2004 Johns Hopkins
Darren S. Gray grad student 2005 Johns Hopkins
Anne Hultgren grad student 2005 Johns Hopkins
John L. Tan grad student 2005 Johns Hopkins
Rowena McBeath grad student 2006 Johns Hopkins
Sami Alom Ruiz grad student 2008 Johns Hopkins
Brian C. DiPaolo grad student 2010 Penn
Zhijun Liu grad student 2010 Penn
Srivatsan Raghavan grad student 2010 Johns Hopkins
Colette Shen grad student 2010 Penn
Ling Dong grad student 2011 Penn
Jennifer L. Leight grad student 2011 Penn
Michael T. Yang grad student 2011 Penn
Ravi A. Desai grad student 2004-2011 Penn
Jan D. Baranski grad student 2012 Penn
Wesley R. Legant grad student 2012 Penn
Brandon L. Blakely grad student 2014 Penn
Anant Chopra post-doc (Physics Tree)
Esak Lee post-doc (Biomechanics Tree)
Joe Tien post-doc 1999-2001 Johns Hopkins Medical School (Biomechanics Tree)
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Publications

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Nguyen DT, Lee E, Alimperti S, et al. (2019) A biomimetic pancreatic cancer on-chip reveals endothelial ablation via ALK7 signaling. Science Advances. 5: eaav6789
Yoon C, Choi C, Stapleton S, et al. (2019) Myosin IIA-mediated forces regulate multicellular integrity during vascular sprouting. Molecular Biology of the Cell. mbcE19020076
Chow MZ, Sadrian SN, Keung W, et al. (2019) Modulation of chromatin remodeling proteins SMYD1 and SMARCD1 promotes contractile function of human pluripotent stem cell-derived ventricular cardiomyocyte in 3D-engineered cardiac tissues. Scientific Reports. 9: 7502
Polacheck WJ, Kutys ML, Tefft JB, et al. (2019) Microfabricated blood vessels for modeling the vascular transport barrier. Nature Protocols
Cheng D, Jayne RK, Tamborini A, et al. (2019) Studies of 3D directed cell migration enabled by direct laser writing of curved wave topography. Biofabrication
Toepfer CN, Sharma A, Cicconet M, et al. (2019) SarcTrack: An Adaptable Software Tool for Efficient Large-Scale Analysis of Sarcomere Function in hiPSC-Cardiomyocytes. Circulation Research
Wang WY, Pearson AT, Kutys ML, et al. (2018) Extracellular matrix alignment dictates the organization of focal adhesions and directs uniaxial cell migration. Apl Bioengineering. 2: 046107
Hassell BA, Goyal G, Lee E, et al. (2018) Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro. Cell Reports. 23: 3698
Longchamp A, Mirabella T, Arduini A, et al. (2018) Amino Acid Restriction Triggers Angiogenesis via GCN2/ATF4 Regulation of VEGF and HS Production. Cell. 173: 117-129.e14
Song HG, Rumma RT, Ozaki CK, et al. (2018) Vascular Tissue Engineering: Progress, Challenges, and Clinical Promise. Cell Stem Cell. 22: 340-354
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