Jim Thorpe

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1996-1999 University of Reading, UK, Earley, England, United Kingdom 
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"Jim Thorpe"
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Hopcroft NH, Thorpe JH, Brogden AL, et al. (2004) Conformational variation of the DNA Holliday junction Acta Crystallographica Section a Foundations of Crystallography. 60: s21-s21
Teixeira SCM, Thorpe JH, Gale BC, et al. (2004) DNA-targeted drugs – untwisting the tangled web of interactions Acta Crystallographica Section a Foundations of Crystallography. 60: s136-s136
Thorpe JH, Gale BC, Teixeira SC, et al. (2003) Conformational and hydration effects of site-selective sodium, calcium and strontium ion binding to the DNA Holliday junction structure d(TCGGTACCGA)(4). Journal of Molecular Biology. 327: 97-109
Thorpe JH, Teixeira SC, Gale BC, et al. (2003) Crystal structure of the complementary quadruplex formed by d(GCATGCT) at atomic resolution. Nucleic Acids Research. 31: 844-9
Teixeira SC, Thorpe JH, Todd AK, et al. (2002) Structural characterisation of bisintercalation in higher-order DNA at a junction-like quadruplex. Journal of Molecular Biology. 323: 167-71
Thorpe JH, Teixeira SC, Gale BC, et al. (2002) Structural characterization of a new crystal form of the four-way Holliday junction formed by the DNA sequence d(CCGGTACCGG)2: sequence versus lattice? Acta Crystallographica. Section D, Biological Crystallography. 58: 567-9
Thorpe JH, Hobbs JR, Todd AK, et al. (2000) Guanine specific binding at a DNA junction formed by d[CG(5-BrU)ACG](2) with a topoisomerase poison in the presence of Co(2+) ions. Biochemistry. 39: 15055-61
Hobbs JR, Thorpe JH, Denny WA, et al. (2000) Guanine-specific binding at an intercalated DNA junction Acta Crystallographica Section a Foundations of Crystallography. 56: s439-s439
Todd AK, Adams A, Powell HR, et al. (1999) Determination by MAD-DM of the structure of the DNA duplex d[ACGTACG(5-BrU)]2 at 1.46 A and 100 K. Acta Crystallographica. Section D, Biological Crystallography. 55: 729-35
Todd AK, Adams A, Thorpe JH, et al. (1999) Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution. Journal of Medicinal Chemistry. 42: 536-40
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