Thomas J Stout, PhD

1986-1992 Chemistry Cornell University, Ithaca, NY, United States 
 1992-1997 University of California, San Francisco, San Francisco, CA 
"Thomas Stout"
Mean distance: (not calculated yet)


Sign in to add mentor
Jon C. Clardy grad student 1986-1992 Cornell
Robert M. Stroud post-doc 1992-1997 UCSF
BETA: Related publications


You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect.

Brinen LS, Stout TJ. (2003) Can mosquitoes be bitten? A new hope for anti-malarial drug design. Structure (London, England : 1993). 11: 1309-10
Costi PM, Rinaldi M, Tondi D, et al. (1999) Phthalein derivatives as a new tool for selectivity in thymidylate synthase inhibition. Journal of Medicinal Chemistry. 42: 2112-24
Stout TJ, Tondi D, Rinaldi M, et al. (1999) Structure-based design of inhibitors specific for bacterial thymidylate synthase. Biochemistry. 38: 1607-17
Stout TJ, Schellenberger U, Santi DV, et al. (1998) Crystal structures of a unique thermal-stable thymidylate synthase from Bacillus subtilis. Biochemistry. 37: 14736-47
Sage CR, Michelitsch MD, Stout TJ, et al. (1998) D221 in thymidylate synthase controls conformation change, and thereby opening of the imidazolidine. Biochemistry. 37: 13893-901
Stout TJ, Sage CR, Stroud RM. (1998) The additivity of substrate fragments in enzyme-ligand binding. Structure (London, England : 1993). 6: 839-48
Sage CR, Rutenber EE, Stout TJ, et al. (1997) An essential role for water in an enzyme reaction mechanism: the crystal structure of the thymidylate synthase mutant E58Q. Biochemistry. 35: 16270-81
Stout TJ, Stroud RM. (1996) The complex of the anti-cancer therapeutic, BW1843U89, with thymidylate synthase at 2.0 A resolution: implications for a new mode of inhibition. Structure (London, England : 1993). 4: 67-77
Stout TJ, Costi MP, Barlocco D, et al. (1996) Structure-based discovery of a new class of enzyme inhibitors Acta Crystallographica Section a Foundations of Crystallography. 52: C207-C207
Sage CR, Rutenber EE, Stout TJ, et al. (1996) Short-circuiting a water-mediated enzyme reaction Acta Crystallographica Section a Foundations of Crystallography. 52: C239-C239
See more...