Yi-Pin Chang

Affiliations: 
1994-1995 Chemical Engineering Feng Chia University, Taiwan 
 1999-2001 Applied Chemistry Chinese Culture University 
 1999-2001 Natural Product Chemistry National Research Institute of Chinese Medicine 
 2001-2008 Chemistry and Biochemistry National Chung Cheng University, Taiwan 
 2008-2011 Chemistry University of Oxford, Oxford, United Kingdom 
 2012-2014 Torrey Pines Institute for Molecular Studies, USA 
 2014-2015 The Forsyth Institute, USA 
 2017- United Biomedical, Inc. 
Area:
Chemical Biology, Peptide Chemistry, Combinatorial Chemistry, Biomolecular Recognition
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"Yi-Pin Chang"
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Publications

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Chang YP, Chu YH. (2014) Mixture-based combinatorial libraries from small individual peptide libraries: a case study on α1-antitrypsin deficiency. Molecules (Basel, Switzerland). 19: 6330-48
Chang YP, Banerjee J, Dowell C, et al. (2014) Discovery of a potent and selective α3β4 nicotinic acetylcholine receptor antagonist from an α-conotoxin synthetic combinatorial library. Journal of Medicinal Chemistry. 57: 3511-21
Chang YP, Chu YH. (2013) Blocking formation of large protein aggregates by small peptides. Chemical Communications (Cambridge, England). 49: 4591-600
Cheng CI, Chang YP, Chu YH. (2012) Biomolecular interactions and tools for their recognition: focus on the quartz crystal microbalance and its diverse surface chemistries and applications. Chemical Society Reviews. 41: 1947-71
Chang YP, Mahadeva R, Patschull AO, et al. (2011) Targeting serpins in high-throughput and structure-based drug design. Methods in Enzymology. 501: 139-75
Chang YP, Mahadeva R, Chang WS, et al. (2009) Small-molecule peptides inhibit Z alpha1-antitrypsin polymerization. Journal of Cellular and Molecular Medicine. 13: 2304-16
Tseng MC, Chang YP, Chu YH. (2007) Quantitative measurements of vancomycin binding to self-assembled peptide monolayers on chips by quartz crystal microbalance. Analytical Biochemistry. 371: 1-9
Chang YP, Tseng MJ, Chu YH. (2006) Using surface plasmon resonance to directly measure slow binding of low-molecular mass inhibitors to a VanX chip. Analytical Biochemistry. 359: 63-71
Chang YP, Mahadeva R, Chang WS, et al. (2006) Identification of a 4-mer peptide inhibitor that effectively blocks the polymerization of pathogenic Z alpha1-antitrypsin. American Journal of Respiratory Cell and Molecular Biology. 35: 540-8
Chang YP, Chu YH. (2005) Using surface plasmon resonance to directly determine binding affinities of combinatorially selected cyclopeptides and their linear analogs to a streptavidin chip. Analytical Biochemistry. 340: 74-9
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