Eugene G. Mueller, Ph.D.

Affiliations: 
Chemistry University of Delaware, Newark, DE, United States 
Area:
Enzymology
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"Eugene Mueller"
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Publications

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Shi X, Wahlang B, Wei X, et al. (2012) Metabolomic analysis of the effects of polychlorinated biphenyls in nonalcoholic fatty liver disease. Journal of Proteome Research. 11: 3805-15
Miracco EJ, Bogdanov B, Mueller EG. (2011) Unexpected linear ion trap collision-induced dissociation and Fourier transform ion cyclotron resonance infrared multi-photon dissociation fragmentation of a hydrated C-glycoside of 5-fluorouridine formed by the action of the pseudouridine synthases RluA and TruB. Rapid Communications in Mass Spectrometry : Rcm. 25: 2627-32
Miracco EJ, Mueller EG. (2011) The products of 5-fluorouridine by the action of the pseudouridine synthase TruB disfavor one mechanism and suggest another. Journal of the American Chemical Society. 133: 11826-9
McDonald MK, Miracco EJ, Chen J, et al. (2011) The handling of the mechanistic probe 5-fluorouridine by the pseudouridine synthase TruA and its consistency with the handling of the same probe by the pseudouridine synthases TruB and RluA. Biochemistry. 50: 426-36
Mueller EG. (2009) Se-ing into selenocysteine biosynthesis. Nature Chemical Biology. 5: 611-2
Hoang C, Chen J, Vizthum CA, et al. (2006) Crystal structure of pseudouridine synthase RluA: indirect sequence readout through protein-induced RNA structure. Molecular Cell. 24: 535-45
Hamilton CS, Greco TM, Vizthum CA, et al. (2006) Mechanistic investigations of the pseudouridine synthase RluA using RNA containing 5-fluorouridine. Biochemistry. 45: 12029-38
Wright CM, Christman GD, Snellinger AM, et al. (2006) Direct evidence for enzyme persulfide and disulfide intermediates during 4-thiouridine biosynthesis. Chemical Communications (Cambridge, England). 3104-6
Mueller EG. (2006) Trafficking in persulfides: delivering sulfur in biosynthetic pathways. Nature Chemical Biology. 2: 185-94
Hoang C, Hamilton CS, Mueller EG, et al. (2005) Precursor complex structure of pseudouridine synthase TruB suggests coupling of active site perturbations to an RNA-sequestering peripheral protein domain. Protein Science : a Publication of the Protein Society. 14: 2201-6
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