Parents

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David A. Horne grad student 1991-1996 Columbia
 (Determinants for tRNA modification by E. coli pseudoridine synthase I.)
Paul Schimmel post-doc 1996-1999 MIT

Children

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Gregory S. Ducker research assistant 2004-2006 Carleton College
BETA: Related publications

Publications

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Chihade J. (2020) Mitochondrial aminoacyl-tRNA synthetases. The Enzymes. 48: 175-206
Kuhle B, Chihade J, Schimmel P. (2020) Relaxed sequence constraints favor mutational freedom in idiosyncratic metazoan mitochondrial tRNAs. Nature Communications. 11: 969
González-Serrano LE, Chihade JW, Sissler M. (2019) When a common biological role does not imply common disease outcomes: Disparate pathology linked to human mitochondrial aminoacyl-tRNA synthetases. The Journal of Biological Chemistry
Kennicott H, McCurdy C, Makori J, et al. (2019) Pathogenic Mutations in a Human Mitochondrial Enzyme Affect Protein Stability The Faseb Journal. 33
Hilander T, Zhou XL, Konovalova S, et al. (2018) Editing activity for eliminating mischarged tRNAs is essential in mammalian mitochondria. Nucleic Acids Research. 46: 849-860
Fernández-Millán P, Schelcher C, Chihade J, et al. (2016) Transfer RNA: From pioneering crystallographic studies to contemporary tRNA biology. Archives of Biochemistry and Biophysics. 602: 95-105
Euro L, Konovalova S, Asin-Cayuela J, et al. (2015) Structural modeling of tissue-specific mitochondrial alanyl-tRNA synthetase (AARS2) defects predicts differential effects on aminoacylation. Frontiers in Genetics. 6: 21
Hati S, Ziervogel B, Sternjohn J, et al. (2006) Pre-transfer editing by class II prolyl-tRNA synthetase: role of aminoacylation active site in "selective release" of noncognate amino acids. The Journal of Biological Chemistry. 281: 27862-72
Lovato MA, Chihade JW, Schimmel P. (2001) Translocation within the acceptor helix of a major tRNA identity determinant. The Embo Journal. 20: 4846-53
Chihade JW, Brown JR, Schimmel PR, et al. (2000) Origin of mitochondria in relation to evolutionary history of eukaryotic alanyl-tRNA synthetase. Proceedings of the National Academy of Sciences of the United States of America. 97: 12153-7
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