Tanja Schirmeister, Ph.D.

Affiliations: 
1999-2002 Institute of Pharmacy Heidelberg University, Tiffin, OH, United States 
 1999-2002 Institute of Pharmacy Albert-Ludwigs-University Freiburg, Freiburg im Breisgau, Baden-Württemberg, Germany 
 2000-2011 Institut für Pharmazie und Lebensmittelchemie Julius-Maximilans-Universität Würzburg, Würzburg, Bayern, Germany 
 2010- Institut für Pharmazie und Biochemie Johannes Gutenberg Universität Mainz, Germany 
Area:
Medicinal Chemistry, Antiviral Drugs, Antiparasitic Drugs, Protease Inhibitors, Glycosidase Inhibitors, Covalent Enzyme Inhibitors, Peptide Chemistry, Chemistry of Three-membered Heterocycles, Vinyl sulfone Chemistry, Peptidomimetics, Enzyme Kinetics, Enz
Website:
http://www.pharmazie.uni-mainz.de/AK-Schirmeister/67.php
Google:
"Tanja Schirmeister"
Bio:

http://www.cinema.uni-mainz.de/141.php
http://www.pharmazie.uni-mainz.de/AK-Schirmeister/67.php

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Parents

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Hans-Hartwig Otto grad student 1989-1993 Universität Freiburg
 (Enzymatische Hydrolyse E/Z-diastereotoper Diester und E/Z-diastereomerer Monoester)
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Publications

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Maiorana S, Ettari R, Previti S, et al. (2020) Peptidyl Vinyl Ketones Irreversible Inhibitors of Rhodesain: Modifications of the P2 Fragment. Chemmedchem
Klein P, Barthels F, Johe P, et al. (2020) Naphthoquinones as Covalent Reversible Inhibitors of Cysteine Proteases-Studies on Inhibition Mechanism and Kinetics. Molecules (Basel, Switzerland). 25
Klein P, Johe P, Wagner A, et al. (2020) New Cysteine Protease Inhibitors: Electrophilic (Het)arenes and Unexpected Prodrug Identification for the Protease Rhodesain. Molecules (Basel, Switzerland). 25
Barthels F, Marincola G, Marciniak T, et al. (2020) Asymmetric Disulfanylbenzamides as Irreversible and Selective Inhibitors of Staphylococcus aureus Sortase A. Chemmedchem
Millies B, von Hammerstein F, Gellert A, et al. (2019) Proline-based allosteric inhibitors of Zika and Dengue virus NS2B/NS3 proteases. Journal of Medicinal Chemistry
Ettari R, Previti S, Maiorana S, et al. (2019) Optimization strategy of novel peptide-based Michael acceptors for the treatment of Human African Trypanosomiasis. Journal of Medicinal Chemistry
von Hammerstein F, Lauth LM, Hammerschmidt S, et al. (2019) Cis autocatalytic cleavage of glycine-linked Zika virus NS2B-NS3 protease constructs. Febs Letters
Viet KK, Wagner A, Schwickert K, et al. (2019) Structure of the Human TRPML2 Ion Channel Extracytosolic/Lumenal Domain. Structure (London, England : 1993)
Preveti S, Ettari R, Cosconati S, et al. (2017) Development of Novel Peptide-based Michael Acceptors Targeting Rhodesain and Falcipain-2 for the Treatment of Neglected Tropical Diseases (NTDs). Journal of Medicinal Chemistry
Latorre A, Schirmeister T, Kesselring J, et al. (2016) Dipeptidyl Nitroalkenes as Potent Reversible Inhibitors of Cysteine Proteases Rhodesain and Cruzain. Acs Medicinal Chemistry Letters. 7: 1073-1076
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