Brian Seed

Affiliations: 
Genetics Harvard Medical School, Boston, MA, United States 
Area:
rapid identification of interesting genes with methods to study the consequences of their expression in an organismic context
Website:
http://www.fas.harvard.edu/~biophys/Brian_Seed.htm
Google:
"Brian Seed"
Bio:

http://chemicalbiology.mgh.harvard.edu/labs-seed.htm
http://tmg.mgh.harvard.edu/assets/Brian%20Seed%20CV.pdf

Mean distance: 8.1
 
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Parents

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Norman Davidson grad student 1981 Caltech
 (A theoretical study of the representation of genomic sequences in partial digest librarias. Studies of the bacteriophage T4 proximal half tail fiber.)
Tom Maniatis grad student 1981 Caltech
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Publications

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Ennamorati M, Vasudevan C, Clerkin K, et al. (2020) Intestinal microbes influence development of thymic lymphocytes in early life. Proceedings of the National Academy of Sciences of the United States of America
Davidson D, Zhong MC, Pandolfi PP, et al. (2016) The Csk-Associated Adaptor PAG Inhibits Effector T Cell Activation in Cooperation with Phosphatase PTPN22 and Dok Adaptors. Cell Reports. 17: 2776-2788
Singhal PK, Sassi S, Lan L, et al. (2015) Mouse embryonic fibroblasts exhibit extensive developmental and phenotypic diversity. Proceedings of the National Academy of Sciences of the United States of America
Draberova L, Bugajev V, Potuckova L, et al. (2014) Transmembrane adaptor protein PAG/CBP is involved in both positive and negative regulation of mast cell signaling. Molecular and Cellular Biology. 34: 4285-300
Zhou GL, Na SY, Niedra R, et al. (2014) Deficits in receptor-mediated endocytosis and recycling in cells from mice with Gpr107 locus disruption. Journal of Cell Science. 127: 3916-27
Freeman J, Kriston-Vizi J, Seed B, et al. (2012) A high-content imaging workflow to study Grb2 signaling complexes by expression cloning. Journal of Visualized Experiments : Jove
Cho JL, Roche MI, Sandall B, et al. (2012) Enhanced Tim3 activity improves survival after influenza infection. Journal of Immunology (Baltimore, Md. : 1950). 189: 2879-89
Zhou L, Kawate T, Liu X, et al. (2012) STAT6 phosphorylation inhibitors block eotaxin-3 secretion in bronchial epithelial cells. Bioorganic & Medicinal Chemistry. 20: 750-8
Westerberg LS, Meelu P, Baptista M, et al. (2010) Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes. The Journal of Experimental Medicine. 207: 1145-52
Leb VM, Jahn-Schmid B, Kueng HJ, et al. (2009) Modulation of allergen-specific T-lymphocyte function by virus-like particles decorated with HLA class II molecules. The Journal of Allergy and Clinical Immunology. 124: 121-8
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