Alfredo J Guerra
Affiliations: | University of Michigan, Ann Arbor, Ann Arbor, MI |
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Parents
Sign in to add mentor| David P. Giedroc | grad student | 2007-2012 | Indiana University Bloomington |
| Vern Carruthers | post-doc | 2017- | University of Michigan (Microtree) |
| Sean Prigge | post-doc | 2012-2016 | Johns Hopkins Bloomberg School of Public Health (Cell Biology Tree) |
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Publications
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| Gregg B, Guerra AJ, Raverty SA, et al. (2025) induced cytokine release syndrome is critically dependent on the expression of pore-forming Perforin-Like Protein-1. Biorxiv : the Preprint Server For Biology |
| Aghabi D, Sloan M, Gill G, et al. (2023) The vacuolar iron transporter mediates iron detoxification in Toxoplasma gondii. Nature Communications. 14: 3659 |
| Zwicker JD, Smith D, Guerra AJ, et al. (2020) Discovery and Optimization of Triazine Nitrile Inhibitors of Toxoplasma gondii Cathepsin L for the Potential Treatment of Chronic Toxoplasmosis in the CNS. Acs Chemical Neuroscience |
| Roberts AD, Nair SC, Guerra AJ, et al. (2019) Development of a conditional localization approach to control apicoplast protein trafficking in malaria parasites. Traffic (Copenhagen, Denmark) |
| Guerra AJ, Zhang O, Bahr CME, et al. (2018) Structural basis of toxoplasma gondii perforin-like protein 1 membrane interaction and activity during egress. Plos Pathogens. 14: e1007476 |
| Zwicker JD, Diaz NA, Guerra AJ, et al. (2018) Optimization of dipeptidic inhibitors of cathepsin L for improved Toxoplasma gondii selectivity and CNS permeability. Bioorganic & Medicinal Chemistry Letters |
| Guerra AJ, Carruthers VB. (2017) Structural Features of Apicomplexan Pore-Forming Proteins and Their Roles in Parasite Cell Traversal and Egress. Toxins. 9 |
| Afanador GA, Guerra AJ, Swift RP, et al. (2017) A novel lipoate attachment enzyme is shared by Plasmodium and Chlamydia species. Molecular Microbiology |
| Guerra AJ, Afanador GA, Prigge ST. (2017) Crystal structure of lipoate-bound lipoate ligase 1, LipL1, from Plasmodium falciparum. Proteins |
| Guerra AJ, Afandor GA, Swift RP, et al. (2015) Lipoylation Mechanism of P. Falciparum Mitochondrial Proteins Biophysical Journal. 108: 57a |