Corwin M. Nycholat

The Scripps Research Institute, California, USA 
Glycoscience, Organic Chemistry
"Corwin Nycholat"
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M Soledade C. Pedras grad student 1998-2001 University of Saskatchewan
 (M. Sc.)
David R. Bundle grad student 2008 University of Alberta
 (Mapping the protective epitope of an anti-Candida albicans monoclonal antibody using synthetic di- and trisaccharide analogues of (1-2)-β-D-mannopyranoside.)
James C. Paulson post-doc 2008-2011 Scripps Institute
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Duan S, Arlian BM, Nycholat CM, et al. (2021) Nanoparticles Displaying Allergen and Siglec-8 Ligands Suppress IgE-FcεRI-Mediated Anaphylaxis and Desensitize Mast Cells to Subsequent Antigen Challenge. Journal of Immunology (Baltimore, Md. : 1950). 206: 2290-2300
Büll C, Nason R, Sun L, et al. (2021) Probing the binding specificities of human Siglecs by cell-based glycan arrays. Proceedings of the National Academy of Sciences of the United States of America. 118
Wu NC, Otwinowski J, Thompson AJ, et al. (2020) Major antigenic site B of human influenza H3N2 viruses has an evolving local fitness landscape. Nature Communications. 11: 1233
Nycholat CM, Duan S, Knuplez E, et al. (2019) A sulfonamide sialoside analog for targeting Siglec-8 and -F on im-mune cells. Journal of the American Chemical Society
Wu NC, Lv H, Thompson AJ, et al. (2019) Preventing an Antigenically Disruptive Mutation in Egg-Based H3N2 Seasonal Influenza Vaccines by Mutational Incompatibility. Cell Host & Microbe
Bednar KJ, Nycholat CM, Rao TS, et al. (2019) Exploiting CD22 to Selectively Tolerize Autoantibody Producing B-cells in Rheumatoid Arthritis. Acs Chemical Biology
Duan S, Koziol-White CJ, Jester WF, et al. (2019) CD33 recruitment inhibits IgE-mediated anaphylaxis and desensitizes mast cells to allergen. The Journal of Clinical Investigation
Edgar LJ, Kawasaki N, Nycholat CM, et al. (2018) Targeted Delivery of Antigen to Activated CD169 Macrophages Induces Bias for Expansion of CD8 T Cells. Cell Chemical Biology
Wu NC, Thompson AJ, Xie J, et al. (2018) A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nature Communications. 9: 1264
Sun Y, Hong S, Xie R, et al. (2018) Mechanistic Investigation and Multiplexing of Liposome-Assisted Metabolic Glycan Labeling. Journal of the American Chemical Society
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