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Bijoy J Desai

Affiliations: 
University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Biochemistry, Enzymology, Biophysics
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Parents

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John A. Gerlt grad student 2009-2014 UIUC
Ruben L. Gonzalez, Jr research scientist 2016- Columbia
Andrew D. Ellington research scientist 2015-2016 UT Austin (Cell Biology Tree)

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Publications

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Desai BJ, Goto Y, Cembran A, et al. (2014) Investigating the role of a backbone to substrate hydrogen bond in OMP decarboxylase using a site-specific amide to ester substitution. Proceedings of the National Academy of Sciences of the United States of America. 111: 15066-71
Kellett WF, Brunk E, Desai BJ, et al. (2013) Computational, structural, and kinetic evidence that Vibrio vulnificus FrsA is not a cofactor-independent pyruvate decarboxylase. Biochemistry. 52: 1842-4
Desai BJ, Wood BM, Fedorov AA, et al. (2012) Conformational changes in orotidine 5′-monophosphate decarboxylase: A structure-based explanation for how the 5′-phosphate group activates the enzyme Biochemistry. 51: 8665-8678
Amyes TL, Ming SA, Goldman LM, et al. (2012) Orotidine 5′-monophosphate decarboxylase: Transition state stabilization from remote protein-phosphodianion interactions Biochemistry. 51: 4630-4632
Iiams V, Desai BJ, Fedorov AA, et al. (2011) Mechanism of the orotidine 5′-monophosphate decarboxylase-catalyzed reaction: Importance of residues in the orotate binding site Biochemistry. 50: 8497-8507
Desai BJ, Boothello RS, Mehta AY, et al. (2011) Interaction of thrombin with sucrose octasulfate. Biochemistry. 50: 6973-82
Prashantha Kumar BR, Sopna S, Verghese J, et al. (2011) Rigid and flexible docking studies on PPAR-γ agonists: key interactions for a better antihyperglycemic activity and in silico pharmacodynamic activity versus experimental in vivo activity Medicinal Chemistry Research. 21: 624-633
Nanjan M, Praveen T, Suresh B, et al. (2008) CoMFA Study on Thiazolidine-2,4-diones for their Antihyperglycemic Activity Letters in Drug Design & Discovery. 5: 79-87
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