Alejandra Herrera-Morande

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2017- Department of Biology Universidad de Chile, Santiago, Región Metropolitana, Chile 
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"Alejandra Herrera-Morande"
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Publications

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Herrera-Morandé A, Vallejos-Baccelliere G, Cea PA, et al. (2023) Kinetic characterization and phylogenetic analysis of human ADP-dependent glucokinase reveal new insights into its regulatory properties. Archives of Biochemistry and Biophysics. 741: 109602
Zamora RA, Fuentes-Lemus E, Barrias P, et al. (2020) Free radicals derived from γ-radiolysis of water and AAPH thermolysis mediate oxidative crosslinking of eGFP involving Tyr-Tyr and Tyr-Cys bonds: the fluorescence of the protein is conserved only towards peroxyl radicals. Free Radical Biology & Medicine. 150: 40-52
Zamora RA, Ramirez-Sarmiento CA, Castro-Fernández V, et al. (2020) Tuning of Conformational Dynamics Through Evolution-Based Design Modulates the Catalytic Adaptability of an Extremophilic Kinase Acs Catalysis. 10847-10857
Herrera-Morande A, Castro-Fernández V, Merino F, et al. (2018) Protein topology determines substrate-binding mechanism in homologous enzymes. Biochimica Et Biophysica Acta. General Subjects. 1862: 2869-2878
Castro-Fernandez V, Herrera-Morande A, Zamora R, et al. (2017) Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases. The Journal of Biological Chemistry. 292: 21218
Castro-Fernandez V, Herrera-Morande A, Zamora R, et al. (2017) Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases. The Journal of Biological Chemistry
Castro-Fernandez V, Bravo-Moraga F, Herrera-Morande A, et al. (2014) Bifunctional ADP-dependent phosphofructokinase/glucokinase activity in the order Methanococcales--biochemical characterization of the mesophilic enzyme from Methanococcus maripaludis. The Febs Journal. 281: 2017-29
Rivas-Pardo JA, Herrera-Morande A, Castro-Fernandez V, et al. (2013) Crystal structure, SAXS and kinetic mechanism of hyperthermophilic ADP-dependent glucokinase from Thermococcus litoralis reveal a conserved mechanism for catalysis. Plos One. 8: e66687
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