Ryuya Fukunaga

2013- Biological Chemistry Johns Hopkins University School of Medicine, Baltimore, MD, United States 
RNA silencing mechanism
"Ryuya Fukunaga"
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Zhu L, Liao SE, Fukunaga R. (2019) Regnase-1 RNase is required for mRNA and miRNA profile remodeling during larva-to-adult metamorphosis. Rna Biology
Zhu L, Liao SE, Ai Y, et al. (2019) RNA methyltransferase BCDIN3D is crucial for female fertility and miRNA and mRNA profiles in Drosophila ovaries. Plos One. 14: e0217603
Liao SE, Kandasamy SK, Zhu L, et al. (2019) DEAD-box RNA helicase Belle post-transcriptionally promotes gene expression in an ATPase activity-dependent manner. Rna (New York, N.Y.)
Zhu L, Kandasamy SK, Liao SE, et al. (2018) LOTUS domain protein MARF1 binds CCR4-NOT deadenylase complex to post-transcriptionally regulate gene expression in oocytes. Nature Communications. 9: 4031
Liao SE, Ai Y, Fukunaga R. (2018) An RNA-binding protein Blanks plays important roles in defining small RNA and mRNA profiles in testes. Heliyon. 4: e00706
Fukunaga R. (2018) Loquacious-PD removes phosphate inhibition of Dicer-2 processing of hairpin RNAs into siRNAs. Biochemical and Biophysical Research Communications. 498: 1022-1027
Zhu L, Kandasamy SK, Fukunaga R. (2018) Dicer partner protein tunes the length of miRNAs using base-mismatch in the pre-miRNA stem. Nucleic Acids Research
Liao SE, Fukunaga R. (2018) Kinetic Analysis of Small Silencing RNA Production by Human and Drosophila Dicer Enzymes In Vitro. Methods in Molecular Biology (Clifton, N.J.). 1680: 101-121
Kandasamy SK, Zhu L, Fukunaga R. (2017) The C-terminal dsRNA-binding domain of Drosophila Dicer-2 is crucial for efficient and high-fidelity production of siRNA and loading of siRNA to Argonaute2. Rna (New York, N.Y.)
Kandasamy SK, Fukunaga R. (2016) Phosphate-binding pocket in Dicer-2 PAZ domain for high-fidelity siRNA production. Proceedings of the National Academy of Sciences of the United States of America. 113: 14031-14036
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