James Karlo Nunez

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Website:
https://weissmanlab.ucsf.edu/people/people.html
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"James Karlo Nunez"
Bio:

https://escholarship.org/uc/item/26n3b6f5

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Parents

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Jennifer A. Doudna grad student 2012-2016 UC Berkeley
 (Mechanism of CRISPR-Cas Immunological Memory.)
Jonathan S. Weissman post-doc UCSF
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Publications

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Sunshine S, Puschnik AS, Replogle JM, et al. (2023) Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq. Nature Communications. 14: 6245
Samelson AJ, Tran QD, Robinot R, et al. (2022) BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2. Nature Cell Biology. 24: 24-34
Nuñez JK, Chen J, Pommier GC, et al. (2021) Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing. Cell
Tian R, Samelson AJ, Rezelj VV, et al. (2021) BRD2 inhibition blocks SARS-CoV-2 infection in vitro by reducing transcription of the host cell receptor ACE2. Biorxiv : the Preprint Server For Biology
Chen J, Brunner AD, Cogan JZ, et al. (2020) Pervasive functional translation of noncanonical human open reading frames. Science (New York, N.Y.). 367: 1140-1146
Tak YE, Kleinstiver BP, Nuñez JK, et al. (2017) Inducible and multiplex gene regulation using CRISPR-Cpf1-based transcription factors. Nature Methods
Adamson B, Norman TM, Jost M, et al. (2016) A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 167: 1867-1882.e21
Nuñez JK, Bai L, Harrington LB, et al. (2016) CRISPR Immunological Memory Requires a Host Factor for Specificity. Molecular Cell. 62: 824-33
Nuñez JK, Harrington LB, Doudna JA. (2016) Chemical and Biophysical Modulation of Cas9 for Tunable Genome Engineering. Acs Chemical Biology. 11: 681-8
Wright AV, Nuñez JK, Doudna JA. (2016) Biology and Applications of CRISPR Systems: Harnessing Nature's Toolbox for Genome Engineering. Cell. 164: 29-44
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