Jean Zhao, Ph.D.

Biological Chemistry and Molecular Pharmacology Harvard Medical School, Boston, MA, United States 
PI3K, malignant transformation
"Jean Zhao"
Mean distance: 35622
Cross-listing: Neuro-oncology Tree


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Lukas Baitsch post-doc Harvard Medical School (Neuro-oncology Tree)
Shom Goel post-doc Harvard Medical School (Neuro-oncology Tree)
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Watt AC, Cejas P, DeCristo MJ, et al. (2021) CDK4/6 inhibition reprograms the breast cancer enhancer landscape by stimulating AP-1 transcriptional activity. Nature Cancer. 2: 34-48
Xie S, Ni J, Guo H, et al. (2021) The role of the PIK3CA gene in the development and aging of the brain. Scientific Reports. 11: 291
Xie S, Ni J, McFaline-Figueroa JR, et al. (2020) Divergent Roles of PI3K Isoforms in PTEN-Deficient Glioblastomas. Cell Reports. 32: 108196
Spangle JM, Von T, Pavlick DC, et al. (2020) PIK3CA C-terminal frameshift mutations are novel oncogenic events that sensitize tumors to PI3K-α inhibition. Proceedings of the National Academy of Sciences of the United States of America
Sun B, Mason S, Wilson RC, et al. (2019) Inhibition of the transcriptional kinase CDK7 overcomes therapeutic resistance in HER2-positive breast cancers. Oncogene
Hemmati S, Sinclair T, Tong M, et al. (2019) PI3 kinase alpha and delta promote hematopoietic stem cell activation. Jci Insight. 5
Wen PY, Touat M, Alexander BM, et al. (2019) Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO1801207
Ding L, Kim HJ, Wang Q, et al. (2018) PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer. Cell Reports. 25: 2972-2980.e5
Wang Y, Li BB, Li J, et al. (2018) A Conditional Dependency on MELK for the Proliferation of Triple-Negative Breast Cancer Cells. Iscience. 9: 149-160
Li BB, Qian C, Roberts TM, et al. (2018) Targeted Profiling of RNA Translation. Current Protocols in Molecular Biology. e71
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