Daniel Brayton

Chemistry

Pat J. Farmer	grad student	2006	UC Irvine
(Targeting melanoma via metal based drugs: Dithiocarbamates, disulfiram copper specificity, and thiomaltol ligands.)

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Brayton DF, Tanabe K, Khiterer M, et al. (2006) Oxygenation of zinc dialkyldithiocarbamate complexes: isolation, characterization, and reactivity of the stoichiometric oxygenates. Inorganic Chemistry. 45: 6064-72
Brayton D, Jacobsen FE, Cohen SM, et al. (2006) A novel heterocyclic atom exchange reaction with Lawesson's reagent: a one-pot synthesis of dithiomaltol. Chemical Communications (Cambridge, England). 206-8
Cen D, Brayton D, Shahandeh B, et al. (2004) Disulfiram facilitates intracellular Cu uptake and induces apoptosis in human melanoma cells. Journal of Medicinal Chemistry. 47: 6914-20
Shahandeh B, Brayton DF, Midyett J, et al. (2004) Synthesis and design of metal based drugs targeting melanoma cancer. Pigment Cell Research. 17: 451-451
Cen D, Brayton D, Shahandeh B, et al. (2004) Disulfiram facilitates intracellular copper transport that causes Oxidative stress and cell death in human Melanoma cells. Pigment Cell Research. 17: 444-445
Farmer PJ, Shandaheh B, Brayton D, et al. (2004) Redox properties of Melanin: The effect of metal ions and oxygen on synthetic Melanins and Melanoma in culture. Pigment Cell Research. 17: 434-434