Mark Borris Aldonza

Affiliations: 
Department of Chemical and Biomolecular Engineering Korea Advanced Institute of Science and Technology, Daejeon, South Korea 
Area:
cancer biology, resistance evolution, drug resistance, metastasis, systems pharmacology, chemical biology
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Publications

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Shin SB, Kim DH, Kim DE, et al. (2021) Dual Targeting of EGFR with PLK1 Exerts Therapeutic Synergism in Taxane-Resistant Lung Adenocarcinoma by Suppressing ABC Transporters. Cancers. 13
Aldonza MBD, Reyes RDD, Kim YS, et al. (2021) Chemotherapy confers a conserved secondary tolerance to EGFR inhibition via AXL-mediated signaling bypass Scientific Reports. 11: 8016
Aldonza MBD, Reyes RDD, Kim YS, et al. (2021) Chemotherapy confers a conserved secondary tolerance to EGFR inhibition via AXL-mediated signaling bypass. Scientific Reports. 11: 8016
Aldonza MB, Cha J, Yong I, et al. (2021) Widespread multi-targeted therapy resistance via drug-induced secretome fucosylation Biorxiv
Aldonza MBD, Ku J, Hong JY, et al. (2020) Prior acquired resistance to paclitaxel relays diverse EGFR-targeted therapy persistence mechanisms. Science Advances. 6: eaav7416
Aldonza MBD, Son YS, Sung HJ, et al. (2017) Paraoxonase-1 (PON1) induces metastatic potential and apoptosis escape via its antioxidative function in lung cancer cells. Oncotarget
Aldonza MB, Hong JY, Lee SK. (2017) Paclitaxel-resistant cancer cell-derived secretomes elicit ABCB1-associated docetaxel cross-resistance and escape from apoptosis through FOXO3a-driven glycolytic regulation. Experimental & Molecular Medicine. 49: e286
Aldonza MB, Hong JY, Alinsug MV, et al. (2016) Multiplicity of acquired cross-resistance in paclitaxel-resistant cancer cells is associated with feedback control of TUBB3 via FOXO3a-mediated ABCB1 regulation. Oncotarget
Aldonza MB, Hong JY, Bae SY, et al. (2015) Correction: Suppression of MAPK Signaling and Reversal of mTOR-Dependent MDR1-Associated Multidrug Resistance by 21α-Methylmelianodiol in Lung Cancer Cells. Plos One. 10: e0133922
Aldonza MB, Hong JY, Bae SY, et al. (2015) Suppression of MAPK Signaling and Reversal of mTOR-Dependent MDR1-Associated Multidrug Resistance by 21α-Methylmelianodiol in Lung Cancer Cells. Plos One. 10: e0127841
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