Charles A. Gersbach, Ph.D.

Affiliations: 
Biomedical Engineering Duke University, Durham, NC 
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"Charles Gersbach"
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Publications

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Cosgrove BD, Bounds LR, Taylor CK, et al. (2024) Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness. Biorxiv : the Preprint Server For Biology
Gonzalez TJ, Simon KE, Blondel LO, et al. (2022) Cross-species evolution of a highly potent AAV variant for therapeutic gene transfer and genome editing. Nature Communications. 13: 5947
Beyersdorf JP, Bawage S, Iglesias N, et al. (2022) Robust, Durable Gene Activation In Vivo via mRNA-Encoded Activators. Acs Nano
Pickar-Oliver A, Gough V, Bohning JD, et al. (2021) Full-length Dystrophin Restoration via Targeted Genomic Integration by AAV-CRISPR in a Humanized Mouse Model of Duchenne Muscular Dystrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy
Gemberling MP, Siklenka K, Rodriguez E, et al. (2021) Transgenic mice for in vivo epigenome editing with CRISPR-based systems. Nature Methods
Abdeen AA, Cosgrove BD, Gersbach CA, et al. (2021) Integrating Biomaterials and Genome Editing Approaches to Advance Biomedical Science. Annual Review of Biomedical Engineering
Saha K, Sontheimer EJ, Brooks PJ, et al. (2021) The NIH Somatic Cell Genome Editing program. Nature. 592: 195-204
Kwon JB, Ettyreddy AR, Vankara A, et al. (2020) Gene Editing of Muscle Stem Cells with Adeno-Associated Viral Vectors in a Mouse Model of Duchenne Muscular Dystrophy. Molecular Therapy. Methods & Clinical Development. 19: 320-329
Carullo NVN, Phillips Iii RA, Simon RC, et al. (2020) Enhancer RNAs predict enhancer-gene regulatory links and are critical for enhancer function in neuronal systems. Nucleic Acids Research
Cosgrove BD, Gersbach CA. (2020) Unwinding the Role of FACT in Cas9-based Genome Editing. Molecular Cell. 79: 365-367
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