Charles A. Gersbach, Ph.D.

Affiliations: 
Biomedical Engineering Duke University, Durham, NC 
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Publications

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Butterfield GL, Reisman SJ, Iglesias N, et al. (2025) Gene Regulation Technologies for Gene and Cell Therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy
Butterfield GL, Rohm D, Roberts A, et al. (2025) Characterization of diverse Cas9 orthologs for genome and epigenome editing. Proceedings of the National Academy of Sciences of the United States of America. 122: e2417674122
Rohm D, Black JB, McCutcheon SR, et al. (2025) Activation of the imprinted Prader-Willi syndrome locus by CRISPR-based epigenome editing. Cell Genomics. 5: 100770
Chen J, Su S, Pickar-Oliver A, et al. (2024) Engineered Cas9 variants bypass Keap1-mediated degradation in human cells and enhance epigenome editing efficiency. Nucleic Acids Research
Rohm D, Black JB, McCutcheon SR, et al. (2024) Activation of the imprinted Prader-Willi Syndrome locus by CRISPR-based epigenome editing. Biorxiv : the Preprint Server For Biology
Cosgrove BD, Bounds LR, Taylor CK, et al. (2024) Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness. Biorxiv : the Preprint Server For Biology
Gonzalez TJ, Simon KE, Blondel LO, et al. (2022) Cross-species evolution of a highly potent AAV variant for therapeutic gene transfer and genome editing. Nature Communications. 13: 5947
Beyersdorf JP, Bawage S, Iglesias N, et al. (2022) Robust, Durable Gene Activation In Vivo via mRNA-Encoded Activators. Acs Nano
Pickar-Oliver A, Gough V, Bohning JD, et al. (2021) Full-length Dystrophin Restoration via Targeted Genomic Integration by AAV-CRISPR in a Humanized Mouse Model of Duchenne Muscular Dystrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy
Gemberling MP, Siklenka K, Rodriguez E, et al. (2021) Transgenic mice for in vivo epigenome editing with CRISPR-based systems. Nature Methods
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