William J. Moore

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1991-1995 Chemistry University of Louisville, Louisville, KY, United States 
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Gilbert AM, Bursavich MG, Lombardi S, et al. (2011) 3-(Pyridin-2-yl-ethynyl)benzamide metabotropic glutamate receptor 5 negative allosteric modulators: hit to lead studies. Bioorganic & Medicinal Chemistry Letters. 21: 195-9
Moore WJ, Richard D, Thorarensen A. (2010) An analysis of the diaminopyrimidine patent estates describing spleen tyrosine kinase inhibitors by Rigel and Portola. Expert Opinion On Therapeutic Patents. 20: 1703-22
Crombie AL, Antrilli TM, Campbell BA, et al. (2010) Synthesis and evaluation of azabicyclo[3.2.1]octane derivatives as potent mixed vasopressin antagonists. Bioorganic & Medicinal Chemistry Letters. 20: 3742-5
Moore WJ, Kern JC, Bhat R, et al. (2010) Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides: part II. Bioorganic & Medicinal Chemistry. 18: 190-201
Vu AT, Cohn ST, Terefenko EA, et al. (2009) 3-(Arylamino)-3-phenylpropan-2-olamines as a new series of dual norepinephrine and serotonin reuptake inhibitors. Bioorganic & Medicinal Chemistry Letters. 19: 2464-7
Bodine PV, Stauffer B, Ponce-de-Leon H, et al. (2009) A small molecule inhibitor of the Wnt antagonist secreted frizzled-related protein-1 stimulates bone formation. Bone. 44: 1063-8
Cole DC, Stock JR, Kreft AF, et al. (2009) (S)-N-(5-Chlorothiophene-2-sulfonyl)-beta,beta-diethylalaninol a Notch-1-sparing gamma-secretase inhibitor. Bioorganic & Medicinal Chemistry Letters. 19: 926-9
Moore WJ, Kern JC, Bhat R, et al. (2009) Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides. Journal of Medicinal Chemistry. 52: 105-16
Cole DC, Stock JR, Chopra R, et al. (2008) Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets. Bioorganic & Medicinal Chemistry Letters. 18: 1063-6
Steffan RJ, Matelan E, Ashwell MA, et al. (2006) Control of chronic inflammation with pathway selective estrogen receptor ligands. Current Topics in Medicinal Chemistry. 6: 103-11
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