Thomas M. Harris

Affiliations: 
Chemistry Vanderbilt University, Nashville, TN 
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Minko IG, Jacobs AC, de Leon AR, et al. (2016) Catalysts of DNA Strand Cleavage at Apurinic/Apyrimidinic Sites. Scientific Reports. 6: 28894
Baertschi SW, Jansen PJ, Montgomery RM, et al. (2014) Investigation of the mechanism of racemization of litronesib in aqueous solution: unexpected base-catalyzed inversion of a fully substituted carbon chiral center. Journal of Pharmaceutical Sciences. 103: 2797-808
Harris TM, Harris CM, Kuzma PC, et al. (2012) Biomimetic syntheses of pretetramides. 3. Synthesis of 6-methylpretetramides using a preassembled D ring template. Journal of the American Chemical Society. 110: 6186-92
Harris CM, Stec DF, Christov PP, et al. (2011) Deoxyguanosine forms a bis-adduct with E,E-muconaldehyde, an oxidative metabolite of benzene: implications for the carcinogenicity of benzene. Chemical Research in Toxicology. 24: 1944-56
Harris TM, Harris CM. (2011) The γ-Alkylation and γ-Arylation of Dianions of β-Dicarbonyl Compounds Organic Reactions. 155-212
Kozekov ID, Turesky RJ, Alas GR, et al. (2010) Formation of deoxyguanosine cross-links from calf thymus DNA treated with acrolein and 4-hydroxy-2-nonenal. Chemical Research in Toxicology. 23: 1701-13
Huang H, Dooley PA, Harris CM, et al. (2009) Differential base stacking interactions induced by trimethylene interstrand DNA cross-links in the 5'-CpG-3' and 5'-GpC-3' sequence contexts. Chemical Research in Toxicology. 22: 1810-6
Brown KL, Voehler MW, Magee SM, et al. (2009) Structural perturbations induced by the alpha-anomer of the aflatoxin B(1) formamidopyrimidine adduct in duplex and single-strand DNA. Journal of the American Chemical Society. 131: 16096-107
Huang H, Kim HY, Kozekov ID, et al. (2009) Stereospecific formation of the (R)-gamma-hydroxytrimethylene interstrand N2-dG:N2-dG cross-link arising from the gamma-OH-1,N2-propano-2'-deoxyguanosine adduct in the 5'-CpG-3' DNA sequence. Journal of the American Chemical Society. 131: 8416-24
Minko IG, Kozekov ID, Harris TM, et al. (2009) Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal. Chemical Research in Toxicology. 22: 759-78
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