Robert Tokhunts, PhD, MD.

1999-2004 Forensic Science John Jay College of Criminal Justice, CUNY, New York, NY, United States 
 2006-2012 Pharmacology and Toxicology Geisel School of Medicine at Dartmouth, Hanover, NH, United States 
 2010-2012 Surgical Oncology University of Miami Miller School of Medicine, Miami, FL, United States 
 2012-2014 Neuroscience Johns Hopkins Neuroscience 
 2014-2018 Medicine Geisel School of Medicine at Dartmouth, Hanover, NH, United States 
NMDA excitotoxicity, Heme degradation, Hedgehog Signaling
"Robert Tokhunts"

Geisel School of Medicine at Dartmouth: MD
Johns Hopkins Medicine: Solomon Snyder Department of Neuroscience: Neuroscientist
University of Miami Miller School of Medicine: Visiting Scholar
Geisel School of Medicine at Dartmouth: PhD
NYC Office of Chief Medical Examiner: Forensic Toxicologist
John Jay College of Criminal Justice: Forensic Science, BS: Summa Cum Laude

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Ethan Dmitrovsky grad student 2006-2012 Dartmouth Medical School
David J Robbins grad student 2006-2012 Dartmouth Medical School
Solomon H. Snyder post-doc 2012-2014 Johns Hopkins Medical School/HHMI (Neurotree)
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Long J, Tokhunts R, Old WM, et al. (2015) Identification of a family of fatty-acid-speciated sonic hedgehog proteins, whose members display differential biological properties. Cell Reports. 10: 1280-7
Rao F, Cha J, Xu J, et al. (2014) Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2. Molecular Cell. 54: 119-32
Fei DL, Sanchez-Mejias A, Wang Z, et al. (2012) Hedgehog signaling regulates bladder cancer growth and tumorigenicity. Cancer Research. 72: 4449-58
Singh S, Wang Z, Liang Fei D, et al. (2011) Hedgehog-producing cancer cells respond to and require autocrine Hedgehog activity. Cancer Research. 71: 4454-63
Xiao C, Ogle SA, Schumacher MA, et al. (2010) Hedgehog signaling regulates E-cadherin expression for the maintenance of the actin cytoskeleton and tight junctions. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G1252-65
Tokhunts R, Singh S, Chu T, et al. (2010) The full-length unprocessed hedgehog protein is an active signaling molecule. The Journal of Biological Chemistry. 285: 2562-8
Britton M, Lucas MM, Downey SL, et al. (2009) Selective inhibitor of proteasome's caspase-like sites sensitizes cells to specific inhibition of chymotrypsin-like sites. Chemistry & Biology. 16: 1278-89
Singh S, Tokhunts R, Baubet V, et al. (2009) Sonic hedgehog mutations identified in holoprosencephaly patients can act in a dominant negative manner. Human Genetics. 125: 95-103
Rosmarion K, Tokhunts R, Rothchild R. (2005) Diels-alder adducts of 3,6-dibromophencyclone with symmetrical 1,4-disubstituted-cis-2-butenes: comparisons with the adduct of phencyclone and N-benzylmaleimide, and one-dimensional and two-dimensional nuclear magnetic resonance studies and ab initio structure calculations. Applied Spectroscopy. 59: 366-75
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