David J Robbins
Affiliations: | Experimental and Molecular Medicine | Geisel School of Medicine at Dartmouth, Hanover, NH, United States |
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Publications
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| Ng VH, Spencer Z, Neitzel LR, et al. (2023) The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling. Nature Communications. 14: 6173 |
| Spencer ZT, Ng VH, Benchabane H, et al. (2023) The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6. Nature Communications. 14: 6174 |
| Kassel S, Hanson AJ, Benchabane H, et al. (2023) USP47 deubiquitylates Groucho/TLE to promote Wnt-β-catenin signaling. Science Signaling. 16: eabn8372 |
| Yang F, Wynn DT, Shen C, et al. (2022) Multiprotein GLI Transcriptional Complexes as Therapeutic Targets in Cancer. Life (Basel, Switzerland). 12 |
| Wynn DT, Rodriguez-Blanco J, Long J, et al. (2022) Protein arginine methyltransferase 5 regulates SHH-subgroup medulloblastoma progression. Neuro-Oncology Advances. 4: vdac144 |
| Yang F, Rodriguez-Blanco J, Long J, et al. (2022) A druggable UHRF1/DNMT1/GLI complex regulates Sonic hedgehog dependent tumor growth. Molecular Cancer Research : McR |
| Shen C, Nayak A, Neitzel LR, et al. (2022) The Casein kinase 1α agonist pyrvinium attenuates Wnt-mediated CK1α degradation via interaction with the E3 ubiquitin ligase component Cereblon. The Journal of Biological Chemistry. 102227 |
| Shen C, Nayak A, Neitzel LR, et al. (2021) The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling. Nature Communications. 12: 5263 |
| Alvarez-Trotta A, Guerrant W, Astudillo L, et al. (2021) Pharmacological disruption of the Notch1 transcriptional complex inhibits tumor growth by selectively targeting cancer stem cells. Cancer Research |
| Alvarez-Trotta A, Wang Z, Shersher E, et al. (2020) The bromodomain inhibitor IBET-151 attenuates vismodegib-resistant esophageal adenocarcinoma growth through reduction of GLI signaling. Oncotarget. 11: 3174-3187 |