Xiao Le Kong, PhD

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2004-2008 King's College London, London, UK 
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"Xiao Le Kong"
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Publications

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Zhou T, Kong XL, Hider RC. (2019) Synthesis and iron chelating properties of hydroxypyridinone and hydroxypyranone hexadentate ligands. Dalton Transactions (Cambridge, England : 2003)
Xie YY, Lu Z, Kong XL, et al. (2016) Systematic comparison of the mono-, dimethyl- and trimethyl 3-hydroxy-4(1H)-pyridones - Attempted optimization of the orally active iron chelator, deferiprone. European Journal of Medicinal Chemistry. 115: 132-140
Zhou YJ, Liu MS, Osamah AR, et al. (2015) Hexadentate 3-hydroxypyridin-4-ones with high iron(III) affinity: design, synthesis and inhibition on methicillin resistant Staphylococcus aureus and Pseudomonas strains. European Journal of Medicinal Chemistry. 94: 8-21
Zhang MX, Zhu CF, Zhou YJ, et al. (2014) Design, synthesis, and antimicrobial evaluation of hexadentate hydroxypyridinones with high iron(III) affinity. Chemical Biology & Drug Design. 84: 659-68
Arezes J, Costa M, Vieira I, et al. (2013) Non-transferrin-bound iron (NTBI) uptake by T lymphocytes: evidence for the selective acquisition of oligomeric ferric citrate species. Plos One. 8: e79870
Li DF, Hu PP, Liu MS, et al. (2013) Design and synthesis of hydroxypyridinone-L-phenylalanine conjugates as potential tyrosinase inhibitors. Journal of Agricultural and Food Chemistry. 61: 6597-603
Zhu CF, Qiu DH, Kong XL, et al. (2013) Synthesis and in-vitro antimicrobial evaluation of a high-affinity iron chelator in combination with chloramphenicol. The Journal of Pharmacy and Pharmacology. 65: 512-20
Chen YL, Barlow DJ, Kong XL, et al. (2012) Prediction of 3-hydroxypyridin-4-one (HPO) log K1 values for Fe(III). Dalton Transactions (Cambridge, England : 2003). 41: 10784-91
Chen YL, Barlow DJ, Kong XL, et al. (2012) Prediction of 3-hydroxypyridin-4-one (HPO) hydroxyl pKa values. Dalton Transactions (Cambridge, England : 2003). 41: 6549-57
Xu B, Kong XL, Zhou T, et al. (2011) Synthesis, iron(III)-binding affinity and in vitro evaluation of 3-hydroxypyridin-4-one hexadentate ligands as potential antimicrobial agents. Bioorganic & Medicinal Chemistry Letters. 21: 6376-80
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