Mioara Larion, Ph.D.
Affiliations: | Chemistry & Biochemistry | Florida State University, Tallahassee, FL, United States |
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"Mioara Larion"Mean distance: 9.12 | S | N | B | C | P |
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Sign in to add mentor| Brian G. Miller | grad student | 2009 | Florida State | |
| (Evolution of substrate specificity in the ROK superfamily and the origin of allosteric regulation in human pancreatic glucokinase.) | ||||
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Publications
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| Ruiz-Rodado V, Seki T, Dowdy T, et al. (2020) Metabolic Landscape of a Genetically Engineered Mouse Model of IDH1 Mutant Glioma. Cancers. 12 |
| Yu D, Liu Y, Zhou Y, et al. (2020) Triptolide suppresses IDH1-mutated malignancy via Nrf2-driven glutathione metabolism. Proceedings of the National Academy of Sciences of the United States of America |
| Han S, Liu Y, Cai SJ, et al. (2020) IDH mutation in glioma: molecular mechanisms and potential therapeutic targets. British Journal of Cancer |
| Ren L, Ruiz-Rodado V, Dowdy T, et al. (2020) Glutaminase-1 (GLS1) inhibition limits metastatic progression in osteosarcoma. Cancer & Metabolism. 8: 4 |
| Victor RR, Malta TM, Seki T, et al. (2019) Metabolic Reprogramming Associated with Aggressiveness Occurs in the G-CIMP-High Molecular Subtypes of IDH1mut Lower Grade Gliomas. Neuro-Oncology |
| Yeung C, Gibson AE, Issaq SH, et al. (2019) Targeting glycolysis through inhibition of lactate dehydrogenase impairs tumor growth in preclinical models of Ewing sarcoma. Cancer Research |
| Larion M, Hansen A, Bruschweiler-Li L, et al. (2019) Specific 13CH3 Labeling and NMR Reveal the Role of Structural Dynamics to Enzymatic Function Biophysical Journal. 116: 470a |
| Larion M, Dowdy T, Ruiz-Rodado V, et al. (2018) Detection of Metabolic Changes Induced via Drug Treatments in Live Cancer Cells and Tissue Using Raman Imaging Microscopy. Biosensors. 9 |
| Rodado VR, Lita A, Dowdy T, et al. (2017) Abstract 2508: Profiling the metabolic effects of AGI-5198 treatment on IDH1-mutated gliomas Cancer Research. 77: 2508-2508 |
| Larion M, Miller B, Brüschweiler R. (2015) Conformational heterogeneity and intrinsic disorder in enzyme regulation: Glucokinase as a case study. Intrinsically Disordered Proteins. 3: e1011008 |