Edward Rosfjord, PhD

Affiliations: 
2000- Oncology Pfizer Research Pearl River 
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"Edward Rosfjord"
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Graziani EI, Sung M, Ma D, et al. (2020) . Molecular Cancer Therapeutics
Betts A, Clark T, Jasper P, et al. (2020) Use of translational modeling and simulation for quantitative comparison of PF-06804103, a new generation HER2 ADC, with Trastuzumab-DM1. Journal of Pharmacokinetics and Pharmacodynamics
Mathur D, Root AR, Bugaj-Gaweda B, et al. (2020) A Novel GUCY2C-CD3 T cell Engaging Bispecific construct (PF-07062119) for the Treatment of Gastrointestinal Cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
Zhong W, Myers JS, Wang F, et al. (2020) Comparison of the molecular and cellular phenotypes of common mouse syngeneic models with human tumors. Bmc Genomics. 21: 2
Mathur D, Root A, Bugaj-Gaweda B, et al. (2020) Abstract 2283: A novel GUCY2C - CD3 bispecific engages T cells to induce cytotoxicity in gastrointestinal tumors Immunology
Yao J, Mathur D, Yang S, et al. (2020) Abstract 4549: Evaluation of GUCY2c-CD3 bispecific targeting GI cancers in an orthotopic colorectal tumor model Immunology. 80: 4549-4549
Arensman MD, Yang XS, Leahy DM, et al. (2019) Cystine-glutamate antiporter xCT deficiency suppresses tumor growth while preserving antitumor immunity. Proceedings of the National Academy of Sciences of the United States of America
Sung MS, Hopf C, Upeslacis E, et al. (2018) Abstract 818: NG-HER2 ADC (PF-06804103) is superior to trastuzumab emtansine in a mouse 'avatar' head-to-head clinical trial Cancer Research. 78: 818-818
Sung M, Tan X, Lu B, et al. (2017) Caveolae-mediated endocytosis as a novel mechanism of resistance to trastuzumab emtansine (T-DM1). Molecular Cancer Therapeutics
Damelin M, Bankovich A, Bernstein J, et al. (2017) A PTK7-targeted antibody-drug conjugate reduces tumor-initiating cells and induces sustained tumor regressions. Science Translational Medicine. 9
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