A. A. Leslie GUNATILAKA

Affiliations: 
University of Arizona, Tucson, AZ 
Area:
Natural Products Chemistry, Medicinal Chemistry
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"A. A. Leslie GUNATILAKA"
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Parents

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Derek Harold Richard Barton grad student 1970-1973 Imperial College
 (Continued as a postdoc in 1974)
Carl Djerassi post-doc 1981-1982 Stanford
David G. I. Kingston research scientist 1989-1996 Virginia Tech
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Publications

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Freitas Misakyan MF, Wijeratne EMK, Issa ME, et al. (2021) Structure-Activity Relationships of Withanolides as Antiproliferative Agents for Multiple Myeloma: Comparison of Activity in 2D Models and a 3D Coculture Model. Journal of Natural Products. 84: 2321-2335
Xu YM, Madasu C, Liu MX, et al. (2021) Cycloartane- and Lanostane-Type Triterpenoids from the Resin of AZ-2, a Byproduct of Guayule Rubber Production. Acs Omega. 6: 15486-15498
Tewary P, Brooks AD, Xu YM, et al. (2021) Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins. Cancer Research
Xu GB, Xu YM, Wijeratne EMK, et al. (2021) Cytotoxic Physalins from Aeroponically Grown . Journal of Natural Products
de Amorim MR, Wijeratne EMK, Zhou S, et al. (2020) An epigenetic modifier induces production of 3-(4-oxopyrano)-chromen-2-ones in sp. AST0006, an endophytic fungus of . Tetrahedron. 76
Xu YM, Arnold AE, U Ren JM, et al. (2020) Teratopyrones A-C, Dimeric Naphtho-γ-Pyrones and Other Metabolites from sp. AK1128, a Fungal Endophyte of . Molecules (Basel, Switzerland). 25
Wang C, Wang X, Zhang L, et al. (2020) Intrinsic and Extrinsic Programming of Product Chain Length and Release Mode in Fungal Collaborating Iterative Polyketide Synthases. Journal of the American Chemical Society
Zhou Y, Cai S, Gomez K, et al. (2020) 1-O-Acetylgeopyxin A, a derivative of a fungal metabolite, blocks tetrodotoxin-sensitive voltage-gated sodium, calcium channels and neuronal excitability which correlates with inhibition of neuropathic pain. Molecular Brain. 13: 73
Lacombe J, Cretignier T, Meli L, et al. (2019) Withanolide D Enhances Radiosensitivity of Human Cancer Cells by Inhibiting DNA Damage Non-homologous End Joining Repair Pathway. Frontiers in Oncology. 9: 1468
Liu P, Tian W, Tao S, et al. (2019) Non-covalent NRF2 Activation Confers Greater Cellular Protection than Covalent Activation. Cell Chemical Biology
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