Matthew W Boudreau, Ph.D.

Affiliations: 
2016-2022 Chemistry University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
 2022- Medical Oncology Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, United States 
Area:
Chemistry, Cancer Biology
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"Matthew Boudreau"
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Publications

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Boudreau MW, Hergenrother PJ. (2022) Evolution of 3-(4-hydroxyphenyl)indoline-2-one as a scaffold for potent and selective anticancer activity. Rsc Medicinal Chemistry. 13: 711-725
Boudreau MW, Mulligan MP, Shapiro DJ, et al. (2022) Activators of the Anticipatory Unfolded Protein Response with Enhanced Selectivity for Estrogen Receptor Positive Breast Cancer. Journal of Medicinal Chemistry
Boudreau MW, Duraki D, Wang L, et al. (2021) A small-molecule activator of the unfolded protein response eradicates human breast tumors in mice. Science Translational Medicine. 13
Lundberg AP, Boudreau MW, Selting KA, et al. (2021) Utilizing feline oral squamous cell carcinoma patients to develop NQO1-targeted therapy. Neoplasia (New York, N.Y.). 23: 811-822
Duraki D, Boudreau MW, Wang L, et al. (2020) OR05-05 Lethal ERα-Dependent Hyperactivation of the Unfolded Protein Response Induces Complete Regression Without Recurrence of Primary and Metastatic Breast Cancer Journal of the Endocrine Society. 4
Boudreau MW, Hergenrother PJ, Duraki D, et al. (2020) Abstract P5-05-16: Quantitative regression of estrogen receptor alpha positive breast cancer Cancer Research. 80
Janin M, Ortiz-Barahona V, de Moura MC, et al. (2019) Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program. Acta Neuropathologica
Boudreau MW, Peh J, Hergenrother PJ. (2019) Procaspase-3 Overexpression in Cancer: A Paradoxical Observation with Therapeutic Potential. Acs Chemical Biology
Guney T, Wenderski TA, Boudreau MW, et al. (2018) Synthesis of Benzannulated Medium-ring Lactams via a Tandem Oxidative Dearomatization-Ring Expansion Reaction. Chemistry (Weinheim An Der Bergstrasse, Germany)
Peh J, Boudreau MW, Smith HM, et al. (2018) Overcoming Resistance to Targeted Anticancer Therapies through Small-Molecule-Mediated MEK Degradation. Cell Chemical Biology
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