Robert J. DeVita
Affiliations: | Pharmacology | Icahn School of Medicine at Mount Sinai, New York, NY, United States |
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Sign in to add trainee| Kunal Kumar | post-doc | Mount Sinai School of Medicine | |
| Hailing Li | post-doc | Mount Sinai School of Medicine | |
| Hui Wang | post-doc | Mount Sinai School of Medicine | |
| Chalada Suebsuwong | post-doc | 2017- | Mount Sinai School of Medicine |
| Khoi Q. Huynh | post-doc | 2017-2018 | Mount Sinai School of Medicine |
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Publications
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| Leandro J, Khamrui S, Suebsuwong C, et al. (2022) Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1. Open Biology. 12: 220179 |
| Wang P, Karakose E, Choleva L, et al. (2021) Human Beta Cell Regenerative Drug Therapy for Diabetes: Past Achievements and Future Challenges. Frontiers in Endocrinology. 12: 671946 |
| He Z, Chen L, Catalan-Dibene J, et al. (2021) Food colorants metabolized by commensal bacteria promote colitis in mice with dysregulated expression of interleukin-23. Cell Metabolism |
| Kumar K, Suebsuwong C, Wang P, et al. (2021) DYRK1A Inhibitors as Potential Therapeutics for β-Cell Regeneration for Diabetes. Journal of Medicinal Chemistry |
| Wu K, Huynh KQ, Lu I, et al. (2021) Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Leandro J, Khamrui S, Wang H, et al. (2020) Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex. Acs Chemical Biology |
| Kumar K, Wang P, A Swartz E, et al. (2020) Structure-Activity Relationships and Biological Evaluation of 7-Substituted Harmine Analogs for Human β-Cell Proliferation. Molecules (Basel, Switzerland). 25 |
| Leandro J, Dodatko T, Aten J, et al. (2020) DHTKD1 and OGDH display substrate overlap in cultured cells and form a hybrid 2-oxo acid dehydrogenase complex in vivo. Human Molecular Genetics |
| Ackeifi C, Wang P, Karakose E, et al. (2020) GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration. Science Translational Medicine. 12 |
| Kumar K, Wang P, Wilson J, et al. (2020) Synthesis and Biological Validation of a Harmine-based, Central Nervous System (CNS)-Avoidant, Selective, Human β-Cell Regenerative Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase A (DYRK1A) Inhibitor. Journal of Medicinal Chemistry |