Marlene Ann Jacobson
Affiliations: | Pharmacy | Temple University, Philadelphia, PA, United States |
Area:
drug discovery and preclinical developmentWebsite:
https://moulder.temple.edu/content/dr-marlene-jacobsonGoogle:
"Marlene Ann Jacobson"Bio:
https://www.researchgate.net/profile/Marlene_Jacobson2
https://books.google.com/books?id=KHxUAAAAYAAJ
http://www.bio.brandeis.edu/prLab/formerMembers.html
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Parents
Sign in to add mentor| Roberta F. Colman | grad student | 1984 | University of Delaware | |
| (Distance relationships between the catalytic, GTP and ADP regulatory sites of glutamate dehydrogenase labeled with fluorescent nucleotide analogues.) | ||||
| Gregory A. Petsko | post-doc | 1987 | MIT | |
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Publications
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| Jacobson MA, Kreatsoulas C, Pascarella DM, et al. (2010) The M1 muscarinic receptor allosteric agonists AC-42 and 1-[1'-(2-methylbenzyl)-1,4'-bipiperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one bind to a unique site distinct from the acetylcholine orthosteric site. Molecular Pharmacology. 78: 648-57 |
| O'Brien JA, Lemaire W, Wittmann M, et al. (2004) A novel selective allosteric modulator potentiates the activity of native metabotropic glutamate receptor subtype 5 in rat forebrain. The Journal of Pharmacology and Experimental Therapeutics. 309: 568-77 |
| Jacobson MA, Colman RF. (1984) Evaluation of the intramolecular stacking of the fluorosulfonylbenzoyl derivatives of 1-N6-ethenoadenosine, adenosine, and guanosine Journal of Biological Chemistry. 259: 1454-1460 |
| Jacobson MA, Colman RF. (1984) Isolation and identification of a tyrosyl peptide labeled by 5′-[p-(fluorosulfonyl)benzoyl]-1,N6-ethenoadenosine at a GTP site of glutamate dehydrogenase Biochemistry. 23: 6377-6382 |
| Jacobson MA, Colman RF. (1984) Distance relationships between the catalytic site labeled with 4-(iodoacetamido)salicylic acid and regulatory sites of glutamate dehydrogenase Biochemistry. 23: 3789-3798 |
| Jacobson MA, Colman RF. (1983) Resonance energy transfer between the adenosine 5prime;-diphosphate site of glutamate dehydrogenase and a guanosine 5′-triphosphate site containing a tyrosine labeled with 5′-[p-(Fluorosulfonyl)benzoyl]-1,N6-ethenoadenosine Biochemistry. 22: 4247-4257 |
| Jacobson MA, Colman RF. (1982) Affinity labeling of a guanosine 5′-triphosphate site of glutamate dehydrogenase by a fluorescent nucleotide analogue, 5′-[p-(fluorosulfonyl)benzoyl]-1,N6-ethenoadenosine Biochemistry. 21: 2177-2186 |