David Grahame Hardie
Affiliations: | Molecular Physiology | University of Dundee, Dundee, Scotland, United Kingdom |
Area:
Biochemistry, Cell BiologyWebsite:
https://iubmb.onlinelibrary.wiley.com/doi/pdf/10.1080/15216540701556873Google:
"Hardie, David Grahame"Bio:
https://scholar.google.com/citations?user=ra3rdoUAAAAJ&hl=en
http://hdl.handle.net/10399/1903
Mean distance: (not calculated yet)
Parents
Sign in to add mentor| David John Manners | grad student | 1974 | Heriot-Watt University | |
| (Cereal carbohydrases) | ||||
Children
Sign in to add trainee| Timothy Arthur James Haystead | grad student | 1988 | University of Dundee |
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Publications
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| Hardie DG. (2022) AMP-activated protein kinase - a journey from 1 to 100 downstream targets. The Biochemical Journal. 479: 2327-2343 |
| Thomas EC, Hook SC, Gray A, et al. (2018) Isoform-specific AMPK association with TBC1D1 is reduced by a mutation associated with severe obesity. The Biochemical Journal |
| Fyffe FA, Hawley SA, Gray A, et al. (2018) Cell-Free Assays to Measure Effects of Regulatory Ligands on AMPK. Methods in Molecular Biology (Clifton, N.J.). 1732: 69-86 |
| Lopez-Mejia IC, Lagarrigue S, Giralt A, et al. (2017) CDK4 Phosphorylates AMPKα2 to Inhibit Its Activity and Repress Fatty Acid Oxidation. Molecular Cell. 68: 336-349.e6 |
| Hardie DG, Lin SC. (2017) AMP-activated protein kinase - not just an energy sensor. F1000research. 6: 1724 |
| Ross FA, Hawley SA, Auciello FR, et al. (2017) Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib. Cell Chemical Biology |
| Hawley SA, Ross FA, Gowans GJ, et al. (2014) Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells. The Biochemical Journal. 459: 275-87 |
| Gowans GJ, Hawley SA, Ross FA, et al. (2013) AMP is a true physiological regulator of AMP-activated protein kinase by both allosteric activation and enhancing net phosphorylation. Cell Metabolism. 18: 556-66 |
| Hawley SA, Fullerton MD, Ross FA, et al. (2012) The ancient drug salicylate directly activates AMP-activated protein kinase. Science (New York, N.Y.). 336: 918-22 |
| Fogarty S, Hawley SA, Green KA, et al. (2010) Calmodulin-dependent protein kinase kinase-β activates AMPK without forming a stable complex: Synergistic effects of Ca2+ and AMP Biochemical Journal. 426: 109-118 |